Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria.
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine …

Migraine is a complex disorder characterized by recurrent episodes of headache, and is one
of the most prevalent and disabling neurological disorders. A key feature of migraine is that …

Chronic migraine is a neurological disorder characterized by 15 or more headache days per
month of which at least 8 days show typical migraine features. The process that describes …

Chronic migraine is a common chronic daily headache featured by frequent headache
attacks with at least 15 headache days per month, which brings great disease burden to …

Migraine is a disabling neurological disorder that affects more than one billion people
worldwide. The clinical presentation is characterized by recurrent headache attacks, which …

In recent years, numerous efforts have been made to identify reliable biomarkers useful in
migraine diagnosis and progression or associated with the response to a specific treatment …

Abstract Purpose of Review The purpose of this review is to revise current evidence on
trigemino-vascular system (TVS) neuropeptides as potential biomarkers for chronic primary …

Calcitonin gene-related peptide (CGRP), vasoactive intestinal peptide (VIP) and pituitary
adenylate cyclase activating polypetide-38 (PACAP-38) have relevant roles in migraine …

Introduction: Migraine is a very frequent and disabling neurological disorder. The current
treatment options are old, generally poorly tolerated and not migraine-specific, reflecting the …

The hypothalamus is involved in the regulation of homeostatic mechanisms and migraine-
related trigeminal nociception and as such has been hypothesized to play a central role in …