Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …

Among all neurotrophins, brain-derived neurotrophic factor (BDNF) stands out for its high
level of expression in the brain and its potent effects on synapses. It is now widely accepted …

Using behavioral, pharmacological, and molecular methods, lots of studies reveal that
depression is closely related to the abnormal neural plasticity processes occurring in the …

Our team has been a pioneer in harvesting extracellular vesicles (EVs) enriched for
neuronal origin from peripheral blood and using them as a biomarker discovery platform for …

Neurotrophins are a family of proteins that regulate neuronal survival, synaptic function, and
neurotransmitter release, and elicit the plasticity and growth of axons within the adult central …

Levels of brain-derived neurotrophic factor (BDNF) are reduced in the brain and serum of
depressed patients and at least the reduction in serum levels is reversible upon successful …

Neurotrophic factors, particularly brain-derived neurotrophic factor (BDNF) and other
members of the neurotrophin family, are central mediators of the activity-dependent plasticity …

Brain‐derived neurotrophic factor (BDNF) is a prototypic neurotrophin that regulates diverse
developmental events from the selection of neural progenitors to the terminal dendritic …

Although brain-derived neurotrophic factor (BDNF) regulates numerous and complex
biological processes including memory retention, its extremely low levels in the mature …

Physical activity has received substantial research attention due to its beneficial impact on
cognition in ageing, particularly via the action of brain-derived neurotrophic factor (BDNF). It …