Children bear a substantial burden of suffering when it comes to tuberculosis. Ironically, they
are often left out of the scientific and public health advances that have led to important …

Background Contact investigation, the systematic evaluation of individuals in close contact
with an infectious tuberculosis (TB) patient, is a key active case-finding strategy for global TB …

Importance Contact tracing is a multistep process to limit SARS-CoV-2 transmission. Gaps in
the process result in missed opportunities to prevent COVID-19. Objective To quantify …

Background Tuberculosis is recognised as a major cause of morbidity and mortality in
children, with most cases in children going undiagnosed and resulting in poor outcomes …

Background Observational studies have demonstrated the effectiveness of a
fluoroquinolone-based regimen to treat individuals presumed to be infected with drug …

Background Successful delivery and completion of tuberculosis preventive treatment are
necessary for tuberculosis elimination. Shorter preventive treatment regimens currently have …

Background Household contacts of patients with drug-resistant tuberculosis (TB) are at high
risk for being infected with Mycobacterium tuberculosis and for developing TB disease. To …

Background Appropriate management of people exposed in the home to tuberculosis is
essential to prevent morbidity. These household contacts, particularly children, should …

The burden of tuberculosis (TB) among adolescents and young adults in endemic settings is
poorly characterised. This study aimed to review published and unpublished estimates of …

Disease case definitions are important instruments for clinical care, interventional research,
and surveillance. Therefore, it is concerning that the current case definitions for tuberculosis …