Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes

C Angiolilli, PA Kabala, AM Grabiec… - Annals of the …, 2017 - ard.bmj.com
Objectives Non-selective histone deacetylase (HDAC) inhibitors (HDACi) have
demonstrated anti-inflammatory properties in both in vitro and in vivo models of rheumatoid …

Optimizing clinical workflow using precision medicine and advanced data analytics

K Zhai, MS Yousef, S Mohammed, NI Al-Dewik… - Processes, 2023 - mdpi.com
Precision medicine—of which precision prescribing is a core component—is becoming a
new frontier in today's healthcare. Both artificial intelligence (AI) and machine learning (ML) …

How Do Patients Use Self‐Care to Manage Nonspecific Symptoms Prior to a Cancer Diagnosis? A Rapid Review to Inform Future Interventions to Reduce Delays in …

G Wilson, HR Brewer, JM Flanagan… - European Journal of …, 2024 - Wiley Online Library
Background. A timely diagnosis of cancer is important for patient outcomes. The delay in the
patient interval (time from symptom interpretation to seeking help) is often the longest …

[HTML][HTML] British Gynaecological Cancer Society (BGCS) ovarian, tubal and primary peritoneal cancer guidelines: Recommendations for practice update 2024

E Moss, A Taylor, A Andreou, C Ang, R Arora… - European Journal of …, 2024 - Elsevier
Recommendations are graded as per the Royal College of Obstetricians and
Gynaecologists document, Clinical Governance Advice No. 1: Guidance for the …

Ethical and legal implications of implementing risk algorithms for early detection and screening for oesophageal cancer, now and in the future

T Brigden, C Mitchell, E Redrup Hill, A Hall - Plos one, 2023 - journals.plos.org
Background Oesophageal cancer has significant morbidity and mortality but late diagnosis
is common since early signs of disease are frequently misinterpreted. Project DELTA aims to …

Using online search activity for earlier detection of gynaecological malignancy

JF Barcroft, E Yom-Tov, V Lampos, LB Ellis… - BMC public health, 2024 - Springer
Background Ovarian cancer is the most lethal and endometrial cancer the most common
gynaecological cancer in the UK, yet neither have a screening program in place to facilitate …

Diagnosing cancer in English community pharmacies

SH Bradley, D Jones, S Wood, M Rafiq, C Bradley… - bmj, 2024 - bmj.com
Diagnosing cancer in English community pharmacies | The BMJ Skip to main content Intended
for healthcare professionals Access provided by Google Indexer Subscribe My Account My …

[HTML][HTML] Ovarian cancer symptoms in pre-clinical invasive epithelial ovarian cancer–An exploratory analysis nested within the UK Collaborative Trial of Ovarian …

J Dilley, A Gentry-Maharaj, A Ryan, M Burnell… - Gynecologic …, 2023 - Elsevier
Objective UKCTOCS provides an opportunity to explore symptoms in preclinical invasive
epithelial ovarian cancer (iEOC). We report on symptoms in women with pre-clinical (screen …

Symptom-triggered testing detects early stage and low volume resectable advanced stage ovarian cancer

FLA Kwong, C Kristunas, C Davenport… - International Journal …, 2024 - discovery.ucl.ac.uk
Objective: Symptom-triggered testing for ovarian cancer was introduced to the UK whereby
symptomatic women undergo an ultrasound scan and serum CA125, and are referred to …

[HTML][HTML] “Notification! You May Have Cancer.” Could Smartphones and Wearables Help Detect Cancer Early?

SE Scott, MJ Thompson - JMIR cancer, 2024 - cancer.jmir.org
This viewpoint paper considers the authors' perspectives on the potential role of
smartphones, wearables, and other technologies in the diagnosis of cancer. We believe that …