Multistep Approach Points to Compounds Responsible for the Biological Activity and Safety of Hydrolates from Nine Lamiaceae Medicinal Plants on Human Skin …

K Smiljanić, I Prodić, S Trifunovic, M Krstić Ristivojević… - Antioxidants, 2023 - mdpi.com
As byproducts of essential oil distillation, hydrolates are used in natural
cosmetics/biomedicine due to their beneficial skin effects. However, data on their safety with …

Ultrafast Biomimetic Oxidative Folding of Cysteine‐rich Peptides and Microproteins in Organic Solvents

A Kam, S Loo, Y Qiu, CF Liu… - Angewandte Chemie …, 2024 - Wiley Online Library
Disulfides in peptides and proteins are essential for maintaining a properly folded structure.
Their oxidative folding is invariably performed in an aqueous‐buffered solution. However …

Enhanced antifouling properties of marine antimicrobial peptides by PEGylation

T Lou, X Bai, X He, W Liu, Z Yang, Y Yang… - … in Bioengineering and …, 2023 - frontiersin.org
Covalent immobilisation of antimicrobial peptides (AMPs) on underwater surfaces to combat
marine biofouling is of great interest as it is an efficient, broad-spectrum and environmentally …

Anti-fungal Hevein-like peptides biosynthesized from quinoa cleavable hololectins

S Loo, SV Tay, A Kam, F Tang, JS Fan, D Yang… - Molecules, 2021 - mdpi.com
Chitin-binding hevein-like peptides (CB-HLPs) belong to a family of cysteine-rich peptides
that play important roles in plant stress and defense mechanisms. CB-HLPs are ribosomally …

Ginsentide TP1 protects hypoxia-induced dysfunction and ER stress-linked apoptosis

B Dutta, S Loo, A Kam, SK Sze, JP Tam - Cells, 2023 - mdpi.com
Hypoxia-induced vascular endothelial dysfunction (VED) is a significant contributor to
several severe human diseases, including heart disease, stroke, dementia, and cancer …

Hololectin interdomain linker determines asparaginyl endopeptidase-mediated maturation of antifungal hevein-like peptides in oats

S Loo, SV Tay, A Kam, W Lee, JP Tam - Frontiers in plant science, 2022 - frontiersin.org
Heveins and hevein-containing (hev-) lectins play important roles in stress and pathogenic
responses in plants but cause health concerns in humans. Hev-hololectins contain multiple …

Hyperstable EGF-like bleogen derived from cactus accelerates corneal healing in rats

S Loo, A Kam, JP Tam - Frontiers in Pharmacology, 2022 - frontiersin.org
Corneal scarring reduces corneal transparency, compromises vision, and is a major cause
of vision loss worldwide. Epidermal growth factor (EGF), which is the prototypic member of …

Antifouling performance and mechanism analysis of marine peptide modified aluminum alloy surface

T Lou, X Bai, X He, W Liu, Y Yang, C Yuan - Surface and Coatings …, 2022 - Elsevier
Biofouling, the settlement of nuisance fouling organisms on underwater surfaces, seriously
affects the performance of the ship and the development of the maritime industry. Using …

Traditional uses, phytochemistry profile and biological properties of Jarum Tujuh Bilah, Pereskia bleo: a review

NAH Azizan, F Aris, MT Mat Jalil… - Science Letters …, 2024 - ir.uitm.edu.my
Pereskia bleo is a species that belongs to the family of Cactaceae and is distributed across
Asia, Southeast Asia, and America. This plant grows in regions receiving high annual …

Ginsentide-like coffeetides isolated from coffee waste are cell-penetrating and metal-binding microproteins

JP Tam, J Huang, S Loo, Y Li, A Kam - Molecules, 2023 - mdpi.com
Coffee processing generates a huge amount of waste that contains many natural products.
Here, we report the discovery of a panel of novel cell-penetrating and metal ion-binding …