Cardiovascular disease (CVD) is prevalent worldwide and remains a leading cause of
death. Although substantial progress has been made in the diagnosis and treatment of CVD …

Renalase is a novel flavoprotein, highly expressed in kidney and heart, which metabolizes
catecholamines and catecholamine-like substances via a superoxide (O2–)-dependent …

The cellular mechanisms and signaling network that guide the cardiac disease
pathophysiology are inextricably intertwined, which explains the current scarcity of effective …

Background Blood pressure is acutely regulated by the sympathetic nervous system through
the action of vasoactive hormones such as epinephrine, norepinephrine, and dopamine …

Renalase, a recently discovered flavoprotein, which is strongly expressed in the kidney and
heart, effectively metabolizes catecholamines. It was discovered during the search to identify …

AKI is characterized by increased catecholamine levels and hypertension. Renalase, a
secretory flavoprotein that oxidizes catecholamines, attenuates ischemic injury and the …

Objective: To explore the correlation between the plasma renalase level of coronary artery
disease (CAD) patients and the degree of coronary artery stenosis. Methods: A total of 180 …

Background An increased risk for developing essential hypertension, stroke and diabetes is
associated with single nucleotide gene polymorphisms in renalase, a newly described …

Renalase was discovered as a protein synthesized by the kidney and secreted in blood
where it circulates at a concentration of approximately 3–5 μg/ml. Initial reports suggested …

Renalase is a recently discovered flavoprotein that regulates blood pressure, regulates
sodium and phosphate excretion, and displays cardioprotectant action through a …