Molecular imaging in oncology: Current impact and future directions

SP Rowe, MG Pomper - CA: a cancer journal for clinicians, 2022 - Wiley Online Library
The authors define molecular imaging, according to the Society of Nuclear Medicine and
Molecular Imaging, as the visualization, characterization, and measurement of biological …

Pathophysiology and molecular imaging of diabetic foot infections

K Rubitschung, A Sherwood, AP Crisologo… - International journal of …, 2021 - mdpi.com
Diabetic foot infection is the leading cause of non-traumatic lower limb amputations
worldwide. In addition, diabetes mellitus and sequela of the disease are increasing in …

Sex differences in lung imaging and SARS-CoV-2 antibody responses in a COVID-19 golden Syrian hamster model

S Dhakal, CA Ruiz-Bedoya, R Zhou, PS Creisher… - MBio, 2021 - Am Soc Microbiol
In the coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), more severe outcomes are reported in …

Imaging sensitive and drug-resistant bacterial infection with [11C]-trimethoprim

IK Lee, DA Jacome, JK Cho, V Tu… - The Journal of …, 2023 - Am Soc Clin Investig
BACKGROUND Several molecular imaging strategies can identify bacterial infections in
humans. PET affords the potential for sensitive infection detection deep within the body …

ESKAPE and beyond: the burden of coinfections in the COVID-19 pandemic

MÁ Loyola-Cruz, LU Gonzalez-Avila, A Martínez-Trejo… - Pathogens, 2023 - mdpi.com
The ESKAPE group constitute a threat to public health, since these microorganisms are
associated with severe infections in hospitals and have a direct relationship with high …

Development and preclinical validation of 2-deoxy 2-[18F]fluorocellobiose as an Aspergillus-specific PET tracer

S Shah, J Lai, F Basuli, N Martinez-Orengo… - Science Translational …, 2024 - science.org
The global incidence of invasive fungal infections (IFIs) has increased over the past few
decades, mainly in immunocompromised patients, and is associated with high mortality and …

Chemoenzymatic Syntheses of Fluorine-18-Labeled Disaccharides from [18F] FDG Yield Potent Sensors of Living Bacteria In Vivo

AM Sorlin, M López-Álvarez, SJ Rabbitt… - Journal of the …, 2023 - ACS Publications
Chemoenzymatic techniques have been applied extensively to pharmaceutical
development, most effectively when routine synthetic methods fail. The regioselective and …

High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis

CA Ruiz-Bedoya, F Mota, EW Tucker… - The Journal of …, 2022 - Am Soc Clin Investig
Tuberculous meningitis (TB meningitis) is the most severe form of tuberculosis (TB),
requiring 12 months of multidrug treatment for cure, and is associated with high morbidity …

Imaging joint infections using D-methyl-11C-methionine PET/MRI: initial experience in humans

I Polvoy, Y Seo, M Parker, M Stewart… - European journal of …, 2022 - Springer
Purpose Non-invasive imaging is a key clinical tool for detection and treatment monitoring of
infections. Existing clinical imaging techniques are frequently unable to distinguish infection …

Imaging the Bacterial Cell Wall Using N-Acetyl Muramic Acid-Derived Positron Emission Tomography Radiotracers

SH Lee, JM Kim, M López-Álvarez, C Wang… - ACS …, 2023 - ACS Publications
Imaging infections in patients is challenging using conventional methods, motivating the
development of positron emission tomography (PET) radiotracers targeting bacteria-specific …