The recent introduction of the first FDA approved 3D-printed drug has fuelled interest in 3D
printing technology, which is set to revolutionize healthcare. Since its initial use, this rapid …

Hydroxypropylmethylcellulose (HPMC), also known as Hypromellose, is a traditional
pharmaceutical excipient widely exploited in oral sustained drug release matrix systems …

Innovation in the pharmaceutical industry has been limited for a long time to the research
and development of new active compounds; meanwhile, the structure of the production …

Continuous drug product manufacturing is slowly being implemented in the pharmaceutical
industry. Although the benefits related to the quality and cost of continuous manufacturing …

Abstract Three-dimensional printing (3DP), though developed for nonmedical applications
and once regarded as futuristic only, has recently been deployed for the fabrication of …

This study presents a framework for process and product development on a continuous
direct compression manufacturing platform. A challenging sustained release formulation …

The pharmaceutical industry is continuously overcoming ways to reduce its development
times to market and bring new medicines to patients with the highest quality standards …

Continuous manufacturing of tablets has many advantages, including batch size flexibility,
demand-adaptive scale up or scale down, consistent product quality, small operational foot …

In this work a continuous direct compression process was developed for a low-dosed drug
product. Each unit operation of the GEA CDC-50 system was thoroughly investigated. This …

Pharmaceutical solid oral dosage product manufacturing is a well-established, yet
revolutionizing area. To this end, process analytical technology (PAT) involves …