Nanozymes: classification, catalytic mechanisms, activity regulation, and applications

Y Huang, J Ren, X Qu - Chemical reviews, 2019 - ACS Publications
Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …

Potential therapeutic use of ebselen for COVID-19 and other respiratory viral infections

H Sies, MJ Parnham - Free Radical Biology and Medicine, 2020 - Elsevier
Ebselen is an organoselenium compound exhibiting hydroperoxide-and peroxynitrite-
reducing activity, acting as a glutathione peroxidase and peroxiredoxin enzyme mimetic …

A valence‐engineered self‐cascading antioxidant nanozyme for the therapy of inflammatory bowel disease

Q Wang, C Cheng, S Zhao, Q Liu, Y Zhang… - Angewandte …, 2022 - Wiley Online Library
Antioxidant treatment strategy by scavenging reactive oxygen species (ROS) is a highly
effective disease treatment option. Nanozymes with multiple antioxidant activities can cope …

Design of diselenide-bridged hyaluronic acid nano-antioxidant for efficient ROS scavenging to relieve colitis

J Xu, T Chu, T Yu, N Li, C Wang, C Li, Y Zhang… - Acs Nano, 2022 - ACS Publications
Overproduction of reactive oxygen species (ROS), a key characteristic of inflammatory bowel
disease (IBD), is responsible for dysregulation of signal transduction, inflammatory …

Recent advances in tandem selenocyclization and tellurocyclization with alkenes and alkynes

K Sun, X Wang, C Li, H Wang, L Li - Organic Chemistry Frontiers, 2020 - pubs.rsc.org
Seleno-containing heterocycles exist widely in pharmaceutical molecules and the skeletons
of natural products. The addition of organoselenium to alkenes and alkynes via …

Redox-responsive fluorescent probes with different design strategies

Z Lou, P Li, K Han - Accounts of Chemical Research, 2015 - ACS Publications
Conspectus In an aerobic organism, reactive oxygen species (ROS) are an inevitable
metabolic byproduct. Endogenously produced ROS have a significant role in physiological …

Synthesis of organoselenium compounds with elemental selenium

YT Ma, MC Liu, YB Zhou, HY Wu - Advanced Synthesis & …, 2021 - Wiley Online Library
In the recent decade, growing efforts have been devoted to employing elemental selenium
as a selenium source in organic synthesis. In contrast to unstable, smelly, and toxic previous …

Synthesis and applications of thiosulfonates and selenosulfonates as free-radical reagents

X Wang, J Meng, D Zhao, S Tang, K Sun - Chinese Chemical Letters, 2023 - Elsevier
Chalcogenative sulfones (thiosulfonates and selenosulfonates), as reactants for organic
transformations, are widely used and interesting because of their potential to react with …

Recent advances on reactive oxygen species-responsive delivery and diagnosis system

H Ye, Y Zhou, X Liu, Y Chen, S Duan, R Zhu… - …, 2019 - ACS Publications
Reactive oxygen species (ROS) play crucial roles in biological metabolism and intercellular
signaling. However, ROS level is dramatically elevated due to abnormal metabolism during …

Enzyme mimics: advances and applications

E Kuah, S Toh, J Yee, Q Ma… - Chemistry–A European …, 2016 - Wiley Online Library
Enzyme mimics or artificial enzymes are a class of catalysts that have been actively pursued
for decades and have heralded much interest as potentially viable alternatives to natural …