Glioblastoma multiforme (GBM) is commonly known as the most aggressive primary CNS
tumor in adults. The mean survival of it is 14 to 15 months, following the standard therapy …

Purpose Limited evidence is available on the utility of dose-escalated radiation therapy (DE-
RT) with or without temozolomide (TMZ) versus standard-of-care radiation therapy (SoC-RT) …

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Central Nervous
System (CNS) Cancers provide interdisciplinary recommendations for managing adult CNS …

Background We sought to determine the maximum tolerated dose (MTD) of 5-fraction
stereotactic radiosurgery (SRS) with 5-mm margins delivered with concurrent temozolomide …

Purpose To review clinical outcomes of moderate dose escalation using high-dose radiation
therapy (HDRT) in the setting of concurrent temozolomide (TMZ) in patients with newly …

Purpose We performed a phase 2 trial of neoadjuvant temozolomide (TMZ), followed by
hypofractionated accelerated radiation therapy (HART) with concurrent TMZ, and adjuvant …

High-grade gliomas (HGGs) are the most common primary malignant brain tumors. They
have a high degree of malignancy and show invasive growth. The personal treatment plan …

Purpose Shorter hypofractionated radiation therapy (HF-RT) schedules may have
radiobiological, patient convenience and healthcare resource advantages over …

Background: Hypofractionated radiotherapy (HFR) is sometimes used in the treatment of
glioblastoma multiforme (GBM). The efficacy and safety of HFR is still under investigation …

Background The objective of this study was to evaluate the outcomes of patients with high‐
grade glioma who received treatment with particle radiotherapy. Methods Between June …