Ocular drug delivery: a comprehensive review
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …
Corneal targeted fenticonazole nitrate-loaded novasomes for the management of ocular candidiasis: Preparation, in vitro characterization, ex vivo and in vivo …
The purpose of this manuscript was to develop and optimize Fenticonazole Nitrate (FTN)-
loaded novasomes aiming to enhance drug corneal penetration and to improve its …
loaded novasomes aiming to enhance drug corneal penetration and to improve its …
[HTML][HTML] Spanlastic-laden in situ gel as a promising approach for ocular delivery of Levofloxacin: In-vitro characterization, microbiological assessment, corneal …
The objective of this study was to encapsulate the antibacterial drug levofloxacin
hemihydrate (LF) into spanlastics (SLs) followed by incorporation into gelrite in situ gel to …
hemihydrate (LF) into spanlastics (SLs) followed by incorporation into gelrite in situ gel to …
A comprehensive review on recent nanosystems for enhancing antifungal activity of fenticonazole nitrate from different routes of administration
This review aims to comprehensively highlight the recent nanosystems enclosing
Fenticonazole nitrate (FTN) and to compare between them regarding preparation …
Fenticonazole nitrate (FTN) and to compare between them regarding preparation …
Curcumin-loaded proniosomal gel as a biofreindly alternative for treatment of ocular inflammation: In-vitro and in-vivo assessment
FA Aboali, DA Habib, HM Elbedaiwy… - International Journal of …, 2020 - Elsevier
Ocular inflammation is a natural defensive phenomenon, but, it results in discomfort in the
eye; as well as makes the eye vulnerable to other diseases. The aim of this work is to …
eye; as well as makes the eye vulnerable to other diseases. The aim of this work is to …
Self-assembling lecithin-based mixed polymeric micelles for nose to brain delivery of clozapine: In-vivo assessment of drug efficacy via radiobiological evaluation
FM Elsharkawy, MM Amin… - International Journal …, 2023 - Taylor & Francis
Purpose The research objective is to design intranasal brain targeted CLZ loaded lecithin
based polymeric micelles (CLZ-LbPM) aiming to improve central systemic CLZ …
based polymeric micelles (CLZ-LbPM) aiming to improve central systemic CLZ …
Cubogel as potential platform for glaucoma management
The aim of this work is to survey the potential of cubogel as an ocular dosage form to boost
the corneal permeability of Dorzolamide Hydrochloride DZ; an antiglaucomal drug. DZ …
the corneal permeability of Dorzolamide Hydrochloride DZ; an antiglaucomal drug. DZ …
Statistical optimization of hyaluronic acid enriched ultradeformable elastosomes for ocular delivery of voriconazole via Box-Behnken design: in vitro characterization …
Voriconazole (VCZ) is a well-known broad spectrum triazole antifungal, mainly used orally
and intravenously. The study aimed to formulate VCZ into ultradeformable elastosomes for …
and intravenously. The study aimed to formulate VCZ into ultradeformable elastosomes for …
[HTML][HTML] Augmented glycerosomes as a promising approach against fungal ear infection: Optimization and microbiological, ex vivo and in vivo assessments
In the current study, voriconazole (VCZ) augmented glycerosomes were optimized for topical
otomycosis management according to a 2 3 factorial design, employing a thin film hydration …
otomycosis management according to a 2 3 factorial design, employing a thin film hydration …
Brain targeting efficiency of intranasal clozapine-loaded mixed micelles following radio labeling with Technetium-99m
The research objective is to design intranasal (IN) brain targeted CLZ-loaded polymeric
nanomicellar systems (PNMS) aiming to improve central systemic CLZ bioavailability. Direct …
nanomicellar systems (PNMS) aiming to improve central systemic CLZ bioavailability. Direct …