Background/Aims: Hydrogen selectively neutralizes reactive oxygen species (ROS) and
ameliorates various ROS-induced injuries. Spinal cord injury (SCI) is a serious injury to the …

In order to find multifunction anticancer complexes, three Mn (II) complexes of N-substituted
di (2-pyridylmethyl) amine were characterized and used as agents to interfere with the …

Two new complexes [(Etdpa) MnCl2] and [(Adpa) Mn (Cl)(H2O)](Etdpa= ethyl bis (2-
pyridylmethyl) amino-2-propionate; Adpa= bis (2-pyridylmethyl) amino-2-propionic acid) …

Background Cerium oxide nanoparticles have gained much more attention especially in the
field of nanomedicine. This work represents cerium oxide nanoparticles as a new …

Mitochondria are organelles involved in the production of cellular energy, regulation of Ca
2+ and redox signaling, and are critical for normal functioning of eukaryotic cells. The …

A frequent side effect of many drugs includes the occurrence of cholestatic liver toxicity. Over
the past couple of decades, drug-induced cholestasis has gained considerable attention …

CoQ10 shares a biosynthetic pathway with cholesterol therefore it can be a potential target
of the widely available lipid-lowering agents such as statins. Statins are the most widely …

The concerns about the possible risk of manufactured nanoparticles (NPs) have been raised
recently. Nano-and micro-sized copper oxide (CO and CONP) are widely used in many …

In order to find mitochondria-targeted mimics of catalase that can attenuate the metabolism
of oxygen for cancer chemotherapy, two complexes [Mn (QA) Cl 2] and [Mn (QA)(OAc)(H 2 …

Paraquat is a broad-spectrum contact herbicide that has been encountered worldwide in
several cases of accidental, homicidal, and suicidal poisonings. The pulmonary toxicity of …