J Bariwal, H Ma, GA Altenberg, H Liang - Chemical Society Reviews, 2022 - pubs.rsc.org
Cancer therapy is a significant challenge due to insufficient drug delivery to the cancer cells and non-selective killing of healthy cells by most chemotherapy agents. Nano-formulations …
Nanomedicine is defined as “the application of nanotechnology to medicine, including the use of nanometer-sized carrier materials for facilitating disease diagnosis, disease treatment …
Y Li, Q Bao, S Yang, M Yang, C Mao - View, 2022 - Wiley Online Library
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …
High-density lipoproteins (HDL) are endogenous nanoparticles involved in the transport and metabolism of cholesterol, phospholipids, and triglycerides. HDL is well-known as the …
Enhanced permeability and retention (EPR) and the (over-) expression of angiogenesis- related surface receptors are key features of tumor blood vessels. As a consequence, EPR …
JL Huang, G Jiang, QX Song, X Gu, M Hu… - Nature …, 2017 - nature.com
Hyperactivated Ras regulates many oncogenic pathways in several malignant human cancers including glioblastoma and it is an attractive target for cancer therapies. Ras …
P Zhang, Y Cui, CF Anderson, C Zhang, Y Li… - Chemical Society …, 2018 - pubs.rsc.org
Pathological changes in a diseased site are often accompanied by abnormal activities of various biomolecules in and around the involved cells. Identifying the location and …
Lipoproteins are a set of natural nanoparticles whose main role is the transport of fats within the body. While much work has been done to develop synthetic nanocarriers to deliver …
SD Perrault, WCW Chan - Proceedings of the National …, 2010 - National Acad Sciences
Many small molecular anticancer agents are often ineffective at detecting or treating cancer due to their poor pharmacokinetics. Using nanoparticles as carriers can improve this …