R&D productivity continues to be the industry's grand challenge. We analyzed the R&D
input, output, and outcome of 16 leading research-based pharmaceutical companies over …

Highlights•Rising R&D expenditures reflect ongoing incremental efficiency decline.•Recent
stabilization in R&D efficiency may not indicate structural reversal.•Sustained turnaround in …

Collaboration among various organizations is important for the sustainable creation of new
innovative drugs. Previously, drug discovery was dominated by large pharmaceutical …

This study investigates the impact of firm-specific uncertainty on innovation performance and
how alliances moderate this relationship in the pharmaceutical industry. To reflect drug …

Within the context of the 'go global'strategy, for enabling enterprises to effectively form open
innovation strategies to enhance overseas business income and assume environmental …

Based on the theories of social networks and Knowledge-Based View, this paper explores
the mechanism of top management team network on enterprises' open innovation, using …

Highlights•Gene therapy is becoming established in the treatment of rare diseases.•The
ease of starting clinical development has attracted startups, including those from academia.• …

Innovations in synthetic chemistry have a profound impact on the drug discovery process,
and will always be a necessary driver of drug development. As a result, it is of significance to …

Abstract 'Doing science together'collaborations are a more intense form of university–
industry interactions and are characterized by a mutual involvement and active participation …

Target 2035, an international federation of biomedical scientists from the public and private
sectors, is leveraging 'open'principles to develop a pharmacological tool for every human …