Mitral valve prolapse (MVP) is the most common valve disease in the western world and
recently emerged as a possible substrate for sudden cardiac death (SCD). It is estimated an …

Accurate evaluation of the mitral valve (MV) apparatus is essential for understanding the
mechanisms of MV disease across various clinical scenarios. The mitral annulus (MA) is a …

Background The presence of mitral annulus disjunction (MAD) has been considered a high-
risk feature for sudden cardiac death based on selected study populations. We aimed to …

Mitral annular disjunction (MAD), a separation between the left atrium/mitral valve annulus
and the left ventricular myocardium, is frequently seen in patients with arrhythmic mitral …

Objectives The identification of patients with mitral valve prolapse (MVP) presenting high
arrhythmic risk remains challenging. Cardiovascular Magnetic Resonance (CMR) feature …

Aims Previously, we demonstrated that inferolateral mitral annular disjunction (MAD) is more
prevalent in patients with idiopathic ventricular fibrillation (IVF) than in healthy controls. In …

Myocardial fibrosis involves the loss of cardiomyocytes, myocardial fibroblast proliferation,
and a reduction in angiogenesis, ultimately leading to heart failure, Given its significant …

The 2019 Global Burden of Disease (GBD) study estimated that there were approximately
24.2 million people affected worldwide by degenerative mitral regurgitation (MR), resulting …

Background Recently, an expert consensus statement proposed indications where
implantation of a primary prevention implantable cardioverter-defibrillator (ICD) may be …

Background Clinical importance of mitral annulus disjunction (MAD) is not well established.
Purpose Characterize a population of MAD all‐comers diagnosed by cardiac magnetic …