Single-cell microfluidic impedance cytometry: From raw signals to cell phenotypes using data analytics

C Honrado, P Bisegna, NS Swami, F Caselli - Lab on a Chip, 2021 - pubs.rsc.org
The biophysical analysis of single-cells by microfluidic impedance cytometry is emerging as
a label-free and high-throughput means to stratify the heterogeneity of cellular systems …

Recent advances in the analysis of single cells

L Armbrecht, PS Dittrich - Analytical chemistry, 2017 - ACS Publications
Advances of analytical methods and emerging microfluidic tools have made it possible to
investigate biological processes in living organisms in detail and reach sensitivities sufficient …

A fast impedance-based antimicrobial susceptibility test

DC Spencer, TF Paton, KT Mulroney, TJJ Inglis… - Nature …, 2020 - nature.com
There is an urgent need to develop simple and fast antimicrobial susceptibility tests (ASTs)
that allow informed prescribing of antibiotics. Here, we describe a label-free AST that can …

Review and perspectives on microfluidic flow cytometers

RJ Yang, LM Fu, HH Hou - Sensors and Actuators B: Chemical, 2018 - Elsevier
Modern microflow cytometers are sophisticated instruments capable of measuring multiple
physical characteristics of a single cell simultaneously as the cells flow in suspension …

Microfluidic impedance flow cytometry enabling high-throughput single-cell electrical property characterization

J Chen, C Xue, Y Zhao, D Chen, MH Wu… - International journal of …, 2015 - mdpi.com
This article reviews recent developments in microfluidic impedance flow cytometry for high-
throughput electrical property characterization of single cells. Four major perspectives of …

Advancing Intelligent Organ‐on‐a‐Chip Systems with Comprehensive In Situ Bioanalysis

X Li, H Zhu, B Gu, C Yao, Y Gu, W Xu… - Advanced …, 2024 - Wiley Online Library
In vitro models are essential to a broad range of biomedical research, such as pathological
studies, drug development, and personalized medicine. As a potentially transformative …

Microfluidic impedance cytometry for single-cell sensing: Review on electrode configurations

S Zhu, X Zhang, Z Zhou, Y Han, N Xiang, Z Ni - Talanta, 2021 - Elsevier
Single-cell analysis has gained considerable attention for disease diagnosis, drug
screening, and differentiation monitoring. Compared to the well-established flow cytometry …

Bacteria detection and differentiation using impedance flow cytometry

CH Clausen, M Dimaki, CV Bertelsen, GE Skands… - Sensors, 2018 - mdpi.com
Monitoring of bacteria concentrations is of great importance in drinking water management.
Continuous real-time monitoring enables better microbiological control of the water and …

Lock-in amplifiers as a platform for weak signal measurements: Development and applications

Q Zhang, W Jeong, DJ Kang - Current Applied Physics, 2024 - Elsevier
The accuracy of modern scientific research and technological advancement is highly reliant
on the ability to accurately measure weak signals. The lock-in amplifier (LIA) represents an …

Advances in single cell impedance cytometry for biomedical applications

C Petchakup, KHH Li, HW Hou - Micromachines, 2017 - mdpi.com
Microfluidics impedance cytometry is an emerging research tool for high throughput analysis
of dielectric properties of cells and internal cellular components. This label-free method can …