[HTML][HTML] The SLC9A-C mammalian Na+/H+ exchanger family: molecules, mechanisms, and physiology
SF Pedersen, L Counillon - Physiological reviews, 2019 - journals.physiology.org
Na+/H+ exchangers play pivotal roles in the control of cell and tissue pH by mediating the
electroneutral exchange of Na+ and H+ across cellular membranes. They belong to an …
electroneutral exchange of Na+ and H+ across cellular membranes. They belong to an …
Luminal Na+/H+ exchange in the proximal tubule
IA Bobulescu, OW Moe - Pflügers Archiv-European Journal of Physiology, 2009 - Springer
The proximal tubule is critical for whole-organism volume and acid–base homeostasis by
reabsorbing filtered water, NaCl, bicarbonate, and citrate, as well as by excreting acid in the …
reabsorbing filtered water, NaCl, bicarbonate, and citrate, as well as by excreting acid in the …
Human Clostridium difficile infection: inhibition of NHE3 and microbiota profile
MA Engevik, KA Engevik… - American Journal …, 2015 - journals.physiology.org
Clostridium difficile infection (CDI) is principally responsible for hospital acquired, antibiotic-
induced diarrhea and colitis and represents a significant financial burden on our healthcare …
induced diarrhea and colitis and represents a significant financial burden on our healthcare …
Gut-associated cGMP mediates colitis and dysbiosis in a mouse model of an activating mutation in GUCY2C
Activating mutations in receptor guanylyl cyclase C (GC-C), the target of gastrointestinal
peptide hormones guanylin and uroguanylin, and bacterial heat-stable enterotoxins cause …
peptide hormones guanylin and uroguanylin, and bacterial heat-stable enterotoxins cause …
The role of plasma membrane sodium/hydrogen exchangers in gastrointestinal functions: proliferation and differentiation, fluid/electrolyte transport and barrier integrity
K Nikolovska, UE Seidler, C Stock - Frontiers in Physiology, 2022 - frontiersin.org
The five plasma membrane Na+/H+ exchanger (NHE) isoforms in the gastrointestinal tract
are characterized by distinct cellular localization, tissue distribution, inhibitor sensitivities …
are characterized by distinct cellular localization, tissue distribution, inhibitor sensitivities …
Transcriptional regulation of the intestinal luminal Na+ and Cl− transporters
J Malakooti, S Saksena, RK Gill… - Biochemical …, 2011 - portlandpress.com
The epithelial apical membrane Na+/H+ exchangers [NHE (sodium hydrogen exchanger) 2
and NHE3] and Cl−/HCO3− exchangers [DRA (down-regulated in adenoma) and PAT-1 …
and NHE3] and Cl−/HCO3− exchangers [DRA (down-regulated in adenoma) and PAT-1 …
[HTML][HTML] Apical NA+/H+ exchangers in the mammalian gastrointestinal tract
PR Kiela, H Xu, FK Ghishan - J Physiol Pharmacol, 2006 - jpp.krakow.pl
The Slc9a family of nine Na+/H+ exchangers (NHE) plays a critical role in neutral sodium
absorption in the mammalian intestine as well as other absorptive and secretory epithelia of …
absorption in the mammalian intestine as well as other absorptive and secretory epithelia of …
Lactobacillus acidophilus upregulates intestinal NHE3 expression and function
V Singh, G Raheja, A Borthakur… - American Journal …, 2012 - journals.physiology.org
A major mechanism of electroneutral NaCl absorption in the human ileum and colon
involves coupling of Na+/H+ and Cl−/HCO3− exchangers. Disturbances in these …
involves coupling of Na+/H+ and Cl−/HCO3− exchangers. Disturbances in these …
Solute carrier family 9, subfamily A, member 3 (SLC9A3)/sodium-hydrogen exchanger member 3 (NHE3) dysregulation and dilated intercellular spaces in patients …
C Zeng, S Vanoni, D Wu, JM Caldwell… - Journal of Allergy and …, 2018 - Elsevier
Background Eosinophilic esophagitis (EoE) is characterized by histopathologic
modifications of esophageal tissue, including eosinophil-rich inflammation, basal zone …
modifications of esophageal tissue, including eosinophil-rich inflammation, basal zone …
Involvement of Sp1 and Sp3 in differential regulation of human NHE3 promoter activity by sodium butyrate and IFN-γ/TNF-α
Previously, we reported that IFN-γ and TNF-α downregulate the expression of the human
Na+/H+ exchanger (NHE) 3 gene by modulating Sp1/Sp3 transcription factors in C2BBe1 …
Na+/H+ exchanger (NHE) 3 gene by modulating Sp1/Sp3 transcription factors in C2BBe1 …