[图书][B] Organic synthesis on solid phase: supports, linkers, reactions
FZ Dörwald, FZ Dèorwald - 2002 - Wiley Online Library
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Solid‐phase supports for oligonucleotide synthesis
RT Pon - Current Protocols in Nucleic Acid Chemistry, 2000 - Wiley Online Library
This unit begins with a discussion of the advantages and disadvantages of oligonucleotide
synthesis using solid supports. The physical and chemical properties of solid‐phase …
synthesis using solid supports. The physical and chemical properties of solid‐phase …
Hydroquinone-O,O′-diacetic acid ('Q-linker') as a replacement for succinyl and oxalyl linker arms in solid phase oligonucleotide synthesis
RT Pon, S Yu - Nucleic acids research, 1997 - academic.oup.com
Abstract When hydroquinone-O, O′-diacetic acid is used as a linker arm in solid phase
oligonucleotide synthesis, the time for NH4OH cleavage of oligodeoxy-or …
oligonucleotide synthesis, the time for NH4OH cleavage of oligodeoxy-or …
Fluoride‐cleavable biotinylation phosphoramidite for 5′‐end‐labeling and affinity purification of synthetic oligonucleotides
S Fang, DE Bergstrom - Nucleic acids research, 2003 - academic.oup.com
A fluoride‐cleavable phosphoramidite for biotinylation was designed, synthesized and
coupled efficiently to the 5′‐end of DNA on an automatic synthesizer. The diisopropylsilyl …
coupled efficiently to the 5′‐end of DNA on an automatic synthesizer. The diisopropylsilyl …
Solid-Supported tert-Alkoxycarbonylation Reagents for Anchoring of Amines during Solid Phase Organic Synthesis
AS Hernández, JC Hodges - The Journal of Organic Chemistry, 1997 - ACS Publications
The preparation and characterization of a homologous series of solid phase synthesis resins
for anchoring amines via a Boc-like linker are described. The scope and limitations of these …
for anchoring amines via a Boc-like linker are described. The scope and limitations of these …
Fluoride‐labile protecting groups for the synthesis of base‐sensitive methyl‐SATE oligonucleotide prodrugs
T Guerlavais‐Dagland, A Meyer… - European Journal of …, 2003 - Wiley Online Library
Base‐sensitive methyl‐SATE oligonucleotide prodrugs (prooligos) were synthesized using
fluoride‐labile protection groups on the nucleobases and on certain internucleosidic …
fluoride‐labile protection groups on the nucleobases and on certain internucleosidic …
Hydroquinone-O, O′-diacetic acid as a more labile replacement for succinic acid linkers in solid-phase oligonucleotide synthesis
RT Pon, S Yu - Tetrahedron letters, 1997 - Elsevier
Hydroquinone-O, O′-diacetic acid (QDA) can be used to link nucleosides to CPG or
polystyrene supports instead of succinic acid. Cleavage of oligodeoxy-or …
polystyrene supports instead of succinic acid. Cleavage of oligodeoxy-or …
Protecting groups
K Jarowicki, P Kocienski - Contemporary organic synthesis, 1997 - pubs.rsc.org
Protecting groups Page 1 Protecting groups KRZYSZTOF JAROWICKI and PHILIP KOCIENSKI
Department of Chemistry, University of Glasgow, Glasgow, UK GI2 8QQ Reviewing the …
Department of Chemistry, University of Glasgow, Glasgow, UK GI2 8QQ Reviewing the …
Synthesis and applications of tert-alkoxysiloxane linkers in solid-phase chemistry
MM Meloni, PD White, D Armour, RCD Brown - Tetrahedron, 2007 - Elsevier
Straightforward syntheses of two tert-alkoxysilyl chloride functionalised resins 3 and 31 that
allow facile attachment of 1°, 2°, 3° alcohols and phenols to the solid-phase have been …
allow facile attachment of 1°, 2°, 3° alcohols and phenols to the solid-phase have been …
Polymer‐Supported Synthesis of Oligosaccharides Using a Diisopropylsiloxane Linker and Trichloroacetimidate Donors
M Mar Kayser, JL de Paz, PM Nieto - 2010 - Wiley Online Library
We describe herein the polymer‐supported synthesis of biologically relevant
oligosaccharides using a diisopropylsiloxane linker and trichloroacetimidates as glycosyl …
oligosaccharides using a diisopropylsiloxane linker and trichloroacetimidates as glycosyl …