The nucleus is the largest organelle and is commonly depicted in the center of the cell. Yet
during cell division, migration, and differentiation, it frequently moves to an asymmetric …

During the development of the mammalian central nervous system, neural stem cells and
their derivative progenitor cells generate neurons by asymmetric and symmetric divisions …

Morphogenesis is the remarkable process by which cells self-assemble into complex tissues
and organs that exhibit specialized form and function during embryological development …

Compared with the animal kingdom, fertilization is particularly complex in flowering plants
(angiosperms). Sperm cells of angiosperms have lost their motility and require transportation …

Fertilization triggers a complex cellular programme that transforms two highly specialized
meiotic germ cells, the oocyte and the sperm, into a totipotent mitotic embryo. Linkages …

The nuclear envelope links the cytoskeleton to structural components of the nucleus. It
functions to coordinate nuclear migration and anchorage, organize chromatin, and aid …

Nuclei move to specific locations to polarize migrating and differentiating cells. Many nuclear
movements are microtubule-dependent. However, nuclear movement to reorient the …

Control of the establishment of cell polarity is an essential function in tissue morphogenesis
and renewal that depends on spatial cues provided by the extracellular environment. The …

Layer formation in the developing cerebral cortex requires the movement of neurons from
their site of origin to their final laminar position. We demonstrate, using time-lapse imaging of …

Nuclear movement is critical during neurogenesis and neuronal migration, which are
fundamental for mammalian brain development. Although dynein, Lis1, and other …