Long viewed as an intermediary in protein translation, there is a growing awareness that
transfer RNAs (tRNAs) are capable of myriad other biological functions linked to human …

RNA was shown to have a more substantial role in the regulation of diverse cellular
processes than anticipated until recently. Answers to questions what is the structure of …

How did specific useful protein sequences arise from simpler molecules at the origin of life?
This seemingly needle-in-a-haystack problem has remarkably close resemblance to the old …

As essential components of the protein synthesis machinery, tRNAs undergo a tightly
controlled biogenesis process, which include the incorporation of numerous …

Abstract tRNA is one of the most conserved and abundant RNA species, which plays a key
role during protein translation. tRNA molecules are post-transcriptionally modified by tRNA …

More than 170 post‐transcriptional modifications of RNAs have currently been identified.
Detailed biophysical investigations of these modifications have been limited since large …

Commensal and pathogenic bacteria continuously evolve to survive in diverse ecological
niches by efficiently coordinating gene expression levels in their ever-changing …

Transfer ribonucleic acid (tRNA) therapeutics will provide personalized and mutation
specific medicines to treat human genetic diseases for which no cures currently exist. The …

Pseudouridine is the most frequently naturally occurring RNA modification, found in all
classes of biologically functional RNAs. Compared to uridine, pseudouridine contains an …

Two different mesoporous silica materials (SBA-15 and MCM 41) were impregnated with
four different, commercially available surfactants, namely, E5, PEG 200, C10E6, and Triton X …