Biology of natural killer cells

G Trinchieri - Advances in immunology, 1989 - Elsevier
Publisher Summary Studies of cytotoxicity by human lymphocytes revealed not only that
both allogeneic and syngeneic tumor cells were lysed in a non-MHC-restricted fashion, but …

[PDF][PDF] The T cell receptor/CD3 complex: a dynamic protein ensemble

JC Clevers, B Alarcon, T Wileman… - Annual review of …, 1988 - pure.knaw.nl
A large body of information about antigen receptors on the surface of T lymphocytes has
been gathered in the last five years (1, 2). T cell receptors use a variable region gene pool …

Radiosensitivity of CD4 or CD8 positive human T-lymphocytes by an in vitro colony formation assay

N Nakamura, Y Kusunoki, M Akiyama - Radiation research, 1990 - meridian.allenpress.com
The recent development of an in vitro lymphocyte colony assay makes it possible to examine
variations in the radiosensitivity of humans using peripheral blood lymphocytes (PBL) …

Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes.

S Jonjić, W Mutter, F Weiland, MJ Reddehase… - The Journal of …, 1989 - rupress.org
We have established a murine model system for exploring the ability of a CD4 subset-
deficient host to cope with cytomegalovirus infection, and reported three findings. First, an …

Expression of the γ-δ T-cell receptor on intestinal CD8+ intraepithelial lymphocytes

T Goodman, L Lefrançois - Nature, 1988 - nature.com
The vast majority of mature T lymphocytes in the peripheral blood and lymphoid organs use
the CD3-associated α, β T-cell receptor (TCR) heterodimer for antigen recognition1–3. A …

A major fraction of human intraepithelial lymphocytes simultaneously expresses the γ/δ T cell receptor, the CD8 accessory molecule and preferentially uses the Vδ1 …

K Deusch, F Lüling, K Reich, M Classen… - European journal of …, 1991 - Wiley Online Library
The frequency of T cell receptor (TcR) type and the variable gene segment expression in
human intraepithelial lymphocytes (IEL) from the large intestinal mucosa were studied by …

A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation

Y Chien, M Iwashima, KB Kaplan, JF Elliott, MM Davis - Nature, 1987 - nature.com
A new T-cell receptor gene lies just 5'to the JαCα coding regions. Its placement in this
location suggests a novel mechanism for the regulation of expression of one T-cell receptor …

Live vaccine strain of Francisella tularensis: infection and immunity in mice

AH Fortier, MV Slayter, R Ziemba, MS Meltzer… - Infection and …, 1991 - Am Soc Microbiol
The live vaccine strain (LVS) of Francisella tularensis caused lethal disease in several
mouse strains. Lethality depended upon the dose and route of inoculation. The lethal dose …

Stimulation of a major subset of lymphocytes expressing T cell receptor γδ by an antigen derived from Mycobacterium tuberculosis

RL O'Brien, MP Happ, A Dallas, E Palmer, R Kubo… - Cell, 1989 - cell.com
To investigate the possible function (s) of T cell receptor (TM) y6 expressing lymphocytes,
we generated a series of y? 5 TcR surface positive hybridomas. Spontaneous producers of …

The adult T-cell receptor 5-chain is diverse and distinct from that of fetal thymocytes

J Francis Elliott, EP Rock, PA Patten, MM Davis… - Nature, 1988 - nature.com
T lymphocytes recognize foreign molecules using the T-cell receptor (TCR), a disulphide-
linked heterodimer closely associated with the CD3 polypeptide complex on the cell surface …