Amorphous solid dispersions (ASDs) can increase the oral bioavailability of poorly soluble
drugs. However, their use in drug development is comparably rare due to a lack of basic …

Spray drying is an efficient technology for solid dispersion manufacturing since it allows
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …

From a patient-centric perspective, oromucosal drug delivery is highly attractive due to the
ease of administration without the need of swallowing, and improved patient safety. The aim …

Protein-based amorphous solid dispersions (ASDs) have emerged as a promising approach
for enhancing solubility in comparison to crystalline drugs. The dissolution behavior of …

A title seldom gives exhaustive information about the content it precedes. Consequently, we
sometimes find ourselves disappointed when we realize that a paper is not about what we …

Engineered nanomaterials (ENMs) are an emerging class of contaminants entering
wastewater treatment plants (WWTPs), and standardized testing protocols are needed by …

One of the drawbacks with solid solution systems is their thermodynamic instability in
solution. Considering the release of these systems from extended-release formulations, in …

This study aimed to enhance the dissolution of tadalafil, a poorly water-soluble drug by
applying liquisolid technique. The effects of two critical formulation variables, namely drug …

Amorphization serves as a strategy for the improvement of poor dissolution characteristics of
many drug compounds. However, in many formulations the content of polymeric stabilizer is …

Purpose The ability of water and aqueous solutions to wet relatively nonpolar
pharmaceutical solids during the processing and administration of solid dosage forms is an …