Successful cytosolic delivery of nanomaterials is becoming more and more important, given
the increase in intracellular applications of quantum dots, gold nanoparticles, liposomal drug …

The study of the potential risks associated with the manufacture, use, and disposal of
nanoscale materials, and their mechanisms of toxicity, is important for the continued …

Many different polymers and architectures are now being developed as polymer
therapeutics and non-viral vectors for cytosolic delivery, and cationic dendrimers, and linear …

In the field of nanomedicine, ample attention has been paid to the development of
nanocarriers for the intracellular delivery of therapeutic cargo, such as nucleic acids for gene …

Multidisciplinary research efforts in the field of drug delivery have led to the development of
a variety of drug delivery systems (DDS) designed for site-specific delivery of diagnostic and …

Developments in subcellular fractionation strategies have provided the means to profile and
analyze the protein composition of organelles and cellular structures by proteomics. Here …

A plethora of biological barriers, intended to defend tissues and cells against external
influences, stand in the way of efficient nucleic acid delivery by non-viral nanoplexes. Even …

Lysosomes are an emerging and increasingly important cellular organelle. With every
passing year, more novel proteins and key cellular functions are associated with lysosomes …

Macromolecular therapeutics and nano-sized drug delivery systems often require
localisation to specific intracellular compartments. In particular, efficient endosomal escape …

Quantitative analysis of the intracellular trafficking of nonviral vectors provides critical
information that can guide the rational design of improved cationic systems for gene …