A global review on short peptides: frontiers and perspectives
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …
entities via all domains of life and interfere with protein-protein interactions, which are …
Peptide-drug conjugates: a new hope for cancer management
Cancer remains the leading cause of death worldwide despite advances in treatment
options for patients. As such, safe and effective therapeutics are required. Short peptides …
options for patients. As such, safe and effective therapeutics are required. Short peptides …
Impact of aliphatic acyl and aromatic thioamide substituents on the anticancer activity of Ru (ii)-p-cymene complexes with acylthiourea ligands—in vitro and in vivo …
Six different acylthiourea ligands (L1–L6) and their corresponding Ru (II)-p-cymene
complexes (P1–P6) were designed to explore the structure–activity relationship of the …
complexes (P1–P6) were designed to explore the structure–activity relationship of the …
Cocrystal engineering of pharmaceutical solids: Therapeutic potential and challenges
Cocrystals are an emerging class of crystalline materials composed of two or more different
molecules in the same crystal lattice that are physically connected by non-ionic and non …
molecules in the same crystal lattice that are physically connected by non-ionic and non …
Assessment of the Antioxidant and Antimicrobial Potential of Ptychotis verticillata Duby Essential Oil from Eastern Morocco: An In Vitro and In Silico Analysis
Ptychotis verticillata Duby, referred to as Nûnkha in the local language, is a medicinal plant
that is native to Morocco. This particular plant is a member of the Apiaceae family and has a …
that is native to Morocco. This particular plant is a member of the Apiaceae family and has a …
Cyclic dipeptides: The biological and structural landscape with special focus on the anti-cancer proline-based scaffold
Cyclic dipeptides, also know as diketopiperazines (DKP), the simplest cyclic forms of
peptides widespread in nature, are unsurpassed in their structural and bio-functional …
peptides widespread in nature, are unsurpassed in their structural and bio-functional …
In vitro antioxidant and anti-inflammatory activities of green cardamom essential oil and in silico molecular docking of its major bioactives
Essential oil of Elettaria cardamomum (Green cardamom) is effective in the treatment of
various disease conditions. Globally, Guatemala is the leading producer of green cardamom …
various disease conditions. Globally, Guatemala is the leading producer of green cardamom …
Modeling polyzwitterion-based drug delivery platforms: A perspective of the current state-of-the-art and beyond
S Javan Nikkhah, M Vandichel - ACS Engineering Au, 2022 - ACS Publications
Drug delivery platforms are anticipated to have biocompatible and bioinert surfaces.
PEGylation of drug carriers is the most approved method since it improves water solubility …
PEGylation of drug carriers is the most approved method since it improves water solubility …
The use of machine learning modeling, virtual screening, molecular docking, and molecular dynamics simulations to identify potential VEGFR2 kinase inhibitors
Targeting the signaling pathway of the Vascular endothelial growth factor receptor-2 is a
promising approach that has drawn attention in the quest to develop novel anti-cancer drugs …
promising approach that has drawn attention in the quest to develop novel anti-cancer drugs …
Synthesis and in-silico studies of some new thiazole carboxamide derivatives with theoretical investigation
N A. Kheder, H Ather, D R. Emam… - Polycyclic Aromatic …, 2023 - Taylor & Francis
Based on the tremendous pharmacological activities of compounds containing thiazole and
carboxamide moieties, the current study aims to prepare new series of thiazole, pyrazole …
carboxamide moieties, the current study aims to prepare new series of thiazole, pyrazole …