Ethnopharmacological relevance Rhodiola crenulata is clinically used to combat hypobaric
hypoxia brain injury at high altitude with the function of invigorating Qi and promoting blood …

High potency and safe therapies are still required for ischemic stroke, which is a leading
cause of global death and disability. Herein, a reactive oxygen species (ROS)-responsive …

Ischemic stroke (IS) is a severe neurological disease that is difficult to recovery. Previous
studies have shown that repetitive transcranial magnetic stimulation (rTMS) is a promising …

Ischemic stroke (IS) refers to local brain tissue necrosis which is caused by impaired blood
supply to the carotid artery or vertebrobasilar artery system. As the second leading cause of …

Homoeostatic regulation of the acid–base balance is essential for cellular functional
integrity. However, little is known about the molecular mechanism through which the acid …

Neural stem cells (NSCs) are multipotent stem cells with remarkable self‐renewal potential
and also unique competencies to differentiate into neurons, astrocytes, and …

Zinc (Zn) has antioxidant, anti-inflammatory and anti-proliferative actions, with Zn
dysregulation associated with coronary ischemia/reperfusion injury and smooth muscle cell …

Diabetes is one of the significant risk factors for ischemic stroke. Hyperglycemia exacerbates
the pathogenesis of stroke, leading to more extensive cerebral damage and, as a result, to …

There are few effective and safe neuroprotective agents for the treatment of ischemic stroke
currently. Caffeic acid is a phenolic acid that widely exists in a number of plant species …

Abstract Hydrogen peroxide (H 2 O 2) has been identified recently as a meaningful signaling
molecule. The ability to perform imaging of H 2 O 2 in complex biological organisms with a …