Progress in Biosensors for the Point-of-Care Diagnosis of COVID-19

M Pohanka - Sensors, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a highly virulent infection that has caused a
pandemic since 2019. Early diagnosis of the disease has been recognized as one of the …

SARS-CoV-2 N Protein Induces Acute Lung Injury in Mice via NF-ĸB Activation

J Xia, W Tang, J Wang, D Lai, Q Xu, R Huang… - Frontiers in …, 2021 - frontiersin.org
Background Infection of SARS-CoV-2 may cause acute respiratory syndrome. It has been
reported that SARS-CoV-2 nucleocapsid protein (N-protein) presents early in body fluids …

SARS-CoV-2 RNA and nucleocapsid antigen are blood biomarkers associated with severe disease outcomes that improve in response to remdesivir

K Singh, K Rubenstein, V Callier… - The Journal of …, 2024 - academic.oup.com
Background Although antivirals remain important for the treatment COVID-19, methods to
assess treatment efficacy are lacking. Here, we investigated the impact of remdesivir on viral …

Performance of blood-based nucleocapsid antigen tests for diagnosis of severe acute respiratory syndrome coronavirus 2 infection and infectious viral shedding: A …

S Mathur, M So, P Tahir, MJ Peluso… - Open Forum …, 2023 - academic.oup.com
Data on the performance of blood-based nucleocapsid antigen tests for diagnosing severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and infectious viral …

Platinum-decorated gold nanoparticle-based microfluidic chip immunoassay for ultrasensitive colorimetric detection of SARS-CoV-2 nucleocapsid protein

F Wu, M Mao, L Cai, Q Lin, X Guan… - … Biomaterials Science & …, 2022 - ACS Publications
Gold nanoparticle-based point-of-care tests (POCT) are one of the most widely used
diagnostic tools for SARS-CoV-2 screening. However, the limitation of their insufficient …

RAGE is a receptor for SARS-CoV-2 N protein and mediates N protein–induced acute lung injury

J Xia, J Wang, L Ying, R Huang, K Zhang… - American Journal of …, 2023 - atsjournals.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid protein (N-
protein) increases early in body fluids during infection and has recently been identified as a …

Serum SARS-CoV-2 antigens for the determination of COVID-19 severity

J Favresse, JL Bayart, C David, C Gillot, G Wieërs… - Viruses, 2022 - mdpi.com
The diagnostic of SARS-CoV-2 infection relies on reverse transcriptase polymerase chain
reactions (RT-PCRs) performed on nasopharyngeal (NP) swabs. Nevertheless, false …

Sensitivity and performance of three novel quantitative assays of SARS-CoV-2 nucleoprotein in blood

T Hillig, JR Kristensen, CL Brasen, I Brandslund… - Scientific Reports, 2023 - nature.com
To assess if SARS-CoV-2 (COVID-19) systemic disease can be determined by available
nucleoprotein assays, we compared the performance of three commercial SARS-CoV-2 …

[HTML][HTML] Neopterin and kynurenine in serum and urine as prognostic biomarkers in hospitalized patients with delta and omicron variant SARS-CoV-2 infection

LK Krčmová, K Matoušová, L Javorská… - Clinical Chemistry and …, 2023 - degruyter.com
Objectives Currently, no biomarker or scoring system could clearly identify patients at risk of
progression to a severe coronavirus disease (COVID)-19. Even in patients with known risk …

A Nanoplasmonic Portable Molecular Interaction Platform for High‐Throughput Drug Screening

H Fan, L Huang, R Li, M Chen, J Huang… - Advanced Functional …, 2022 - Wiley Online Library
A fast and reliable method for the detection of molecular interactions in real‐time is
necessary for drug screening and control of infections or diseases. Therefore, this study …