Role of mitochondria in viral infections

S Elesela, NW Lukacs - Life, 2021 - mdpi.com
Viral diseases account for an increasing proportion of deaths worldwide. Viruses maneuver
host cell machinery in an attempt to subvert the intracellular environment favorable for their …

Avian influenza virus tropism in humans

U AbuBakar, L Amrani, FA Kamarulzaman, SA Karsani… - Viruses, 2023 - mdpi.com
An influenza pandemic happens when a novel influenza A virus is able to infect and transmit
efficiently to a new, distinct host species. Although the exact timing of pandemics is …

Influenza A virus PB1-F2 protein: An ambivalent innate immune modulator and virulence factor

PHH Cheung, TWT Lee, CP Chan… - Journal of Leukocyte …, 2020 - academic.oup.com
Influenza A virus (IAV) causes not only seasonal respiratory illness, but also outbreaks of
more severe disease and pandemics when novel strains emerge as a result of reassortment …

Visualizing influenza a virus vRNA replication

YF Chiu, YW Huang, CY Chen, YC Chen… - Frontiers in …, 2022 - frontiersin.org
Influenza A virus (IAV) has caused recurrent epidemics and severe pandemics. In this study,
we adapted an MS2-MCP live-cell imaging system to visualize IAV replication. A reporter …

Age‐Dependent Pathogenesis of Influenza A Virus H7N9 Mediated Through PB1‐F2‐Induced Mitochondrial DNA Release and Activation of cGAS‐STING‐NF‐κB …

PHH Cheung, TL Yuen, TT Tang… - Journal of Medical …, 2024 - Wiley Online Library
Exactly why human infection of avian influenza A virus H7N9 causes more severe disease in
the elderly remains elusive. In this study, we found that H7N9 PB1‐F2 is a pathogenic factor …

TGF-β1 signaling inhibit the in vitro apoptotic, infection and stimulatory cell response induced by influenza H1N1 virus infection on A549 cells

G BustosRivera-Bahena, DV López-Guerrero… - Virus Research, 2021 - Elsevier
Influenza A virus (IAV) infection induces host cell responses that could derive in
inflammatory and apoptotic response. In this respect, in multiple pathological situations, TGF …

[HTML][HTML] PB1-F2 of low pathogenicity H7N7 restricts apoptosis in avian cells

L Hohensee, D Scheibner, C Luttermann, H Shelton… - Virus Research, 2024 - Elsevier
Avian influenza viruses (AIV) pose a continuous challenge to global health and economy.
While countermeasures exist to control outbreaks in poultry, the persistent circulation of AIV …

Avian Influenza Virus Tropism in Humans

UA Bakar, L Amrani, F Kamarulzaman, SA Karsani… - 2023 - preprints.org
A pandemic happens when a novel influenza A virus is able to infect and transmit efficiently
to a new, distinct host species. Although the exact timing of pandemics is uncertain, it is …

A novel protein upstream stimulatory factor 2 identified in lamprey, Lethenteron reissneri

Y Guo, T Li, Q Li, Y Pang, P Su - Development Genes and Evolution, 2020 - Springer
Upstream stimulatory factors are kinds of multi-functional transcription factors, which are
expressed in eukaryotes widely, including Upstream stimulatory factor 1 (USFl) and …

Meta-analysis of RNA Seq Datasets in Duck Lungs Infected with Highly Pathogenic Avian Influenza Viruses

P Vijayakumar, AA Raut, VP Singh, A Mishra - 2023 - indianjournals.com
The molecular mechanisms and hub genes identified for disease resistance in ducks
against highly pathogenic avian influenza virus (HPAIV) infection show substantial …