Altered mitochondrial function is currently recognized as an important factor in
atherosclerosis initiation and progression. Mitochondrial dysfunction can be caused by …

Background. Alzheimer's disease (AD) is the most common cause of dementia in elderly
patients. Recently, several studies have shown that inflammation and oxidative stress …

The budding yeast Saccharomyces cerevisiae, a favorite model in biology, does not contain
any protein of the Bcl-2 family. From initial experiments with two-hybrid systems to the …

Background The glycolytic enzyme, α-Enolase (ENO1), catalyzes the production of
phosphoenolpyruvate from 2-phosphoglycerate, thereby enhancing glycolysis and …

We noticed that during short-term experimental evolution and carcinogenesis, mutations
causing gene inactivation (ie, nonsense mutations or frameshifts) are frequent. Our meta …

The progress of evolutionary biology has revealed that symbiosis played a basic role in the
evolution of complex eukaryotic organisms, including humans. Mitochondria are actually …

Lycopodina hypogea is a carnivorous sponge that tolerates laboratory husbandry very well.
During a digestion cycle, performed without any digestive cavity, this species undergoes …

Background: Adaptor proteins such as growth factor receptor-bound protein-2 (Grb2) play
important roles in cancer cell signaling. In the present study, we examined the biological …

Chronic disease states of aging should be viewed through the prism of metabolism and
biophysical processes at all levels of physiological organization present in the human body …

The glycolytic enzyme, α-Enolase (ENO1), catalyzes the production of phosphoenolpyruvate
from 2-phosphoglycerate, which enhances glycolysis, and thus contributes to tumor …