C–H functionalization reactions are playing an increasing role in the preparation and
modification of complex organic molecules, including pharmaceuticals, agrochemicals and …

Transition-metal catalyzed reactions that are able to construct complex aliphatic amines from
simple, readily available feedstocks have become a cornerstone of modern synthetic …

Radical–radical couplings are mostly nearly diffusion‐controlled processes. Therefore, the
selective cross‐coupling of two different radicals is challenging and not a synthetically …

Research and industrial interest in radical C–H activation/radical cross-coupling chemistry
has continuously grown over the past few decades. These reactions offer fascinating and …

Catalytic transformation of ubiquitous C–H bonds into valuable C–N bonds offers an efficient
synthetic approach to construct N-functionalized molecules. Over the last few decades …

Despite the fact that nucleophilic displacement (SN2) of alkyl halides with nitrogen
nucleophiles is one of the first reactions introduced in organic chemistry teaching, its …

Allylic amines are valuable synthetic targets en route to diverse biologically active amine
products. Current allylic C–H amination strategies remain limited with respect to the viable N …

Copper-catalyzed radical-relay reactions provide a versatile strategy for selective C–H
functionalization; however, reactions with peroxide-based oxidants often require excess C …

The interesting and diverse biological activities of nitrogen-containing compounds make the
construction of the C–N bond of great importance. Despite the tremendous advances that …

Copper is one of the most abundant and less toxic transition metals. Nature takes advantage
of the bioavailability and rich redox chemistry of Cu to carry out oxygenase and oxidase …