[HTML][HTML] Cell death due to electroporation–a review

TB Napotnik, T Polajžer, D Miklavčič - Bioelectrochemistry, 2021 - Elsevier
Exposure of cells to high voltage electric pulses increases transiently membrane
permeability through membrane electroporation. Electroporation can be reversible and is …

High-voltage electrical pulses in oncology: irreversible electroporation, electrochemotherapy, gene electrotransfer, electrofusion, and electroimmunotherapy

B Geboers, HJ Scheffer, PM Graybill, AH Ruarus… - Radiology, 2020 - pubs.rsna.org
This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical
oncology to treat solid tumors with irreversible electroporation (IRE) and …

Irreversible electroporation: background, theory, and review of recent developments in clinical oncology

KN Aycock, RV Davalos - Bioelectricity, 2019 - liebertpub.com
Irreversible electroporation (IRE) has established a clinical niche as an alternative to thermal
ablation for the eradication of unresectable tumors, particularly those near critical vascular …

Irreversible electroporation and electrochemotherapy in oncology: State of the art

JP Tasu, D Tougeron, MP Rols - Diagnostic and Interventional Imaging, 2022 - Elsevier
Thermal tumor ablation techniques including radiofrequency, microwave, LASER, high-
intensity focused ultrasound and cryoablation are routinely used to treated liver, kidney …

Focal irreversible electroporation as primary treatment for localized prostate cancer

W van den Bos, MJ Scheltema… - BJU …, 2018 - Wiley Online Library
Objectives To determine the safety, quality of life (QoL) and short‐term oncological
outcomes of primary focal irreversible electroporation (IRE) for the treatment of localized …

Prostate cancer treatment with Irreversible Electroporation (IRE): Safety, efficacy and clinical experience in 471 treatments

E Guenther, N Klein, S Zapf, S Weil, C Schlosser… - PloS one, 2019 - journals.plos.org
Background Irreversible Electroporation (IRE) is a novel image-guided tissue ablation
technology that induces cell death via very short but strong pulsed electric fields. IRE has …

Oncological and quality-of-life outcomes following focal irreversible electroporation as primary treatment for localised prostate cancer: a biopsy-monitored prospective …

A Blazevski, MJ Scheltema, B Yuen, N Masand… - European urology …, 2020 - Elsevier
Background Focal irreversible electroporation (IRE) can be used to treat men with localised
prostate cancer (PCa) with reduced impact on quality of life (QoL). Objective To assess …

Nanoknife electroporation ablation trial: a prospective development study investigating focal irreversible electroporation for localized prostate cancer

M Valerio, L Dickinson, A Ali, N Ramachadran… - The Journal of …, 2017 - auajournals.org
Purpose: Irreversible electroporation has attractive attributes for focal ablation, namely
nonthermal effect, precise demarcation of treatment and tissue selectivity. We report a …

Irreversible electroporation (IRE): a narrative review of the development of IRE from the laboratory to a prostate cancer treatment

A Blazevski, MJ Scheltema, A Amin… - BJU …, 2020 - Wiley Online Library
Introduction Whilst whole‐gland radical treatment is highly effective for prostate cancer
control, it has significant impact on quality of life and is unnecessary 'over‐treatment'in many …

Boosting the Immune Response—Combining Local and Immune Therapy for Prostate Cancer Treatment

J Karwacki, A Kiełbik, W Szlasa, N Sauer, K Kowalczyk… - Cells, 2022 - mdpi.com
Due to its slow progression and susceptibility to radical forms of treatment, low-grade PC is
associated with high overall survival (OS). With the clinical progression of PC, the therapy is …