Organoids, intricate three-dimensional tissue assemblies derived from either pluripotent or
adult stem cells cultured under laboratory conditions, emerge as a captivating model and …

Cell-based therapy is emerging as a promising strategy for treating a wide range of human
diseases, such as diabetes, blood disorders, acute liver failure, spinal cord injury, and …

Islet transplantation has poor long-term efficacy because of the lack of extracellular matrix
support and neovascularization; this limits its wide application in diabetes research. In this …

Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin-producing β cells
located in the endocrine pancreas in areas known as islets of Langerhans. The current …

Introduction: The disciplines of 3D bioprinting and surgery have witnessed incremental
transformations over the last century. 3D bioprinting is a convergence of biology and …

Cell therapy has already had an important impact on healthcare and provided new
treatments for previously intractable diseases. Notable examples include mesenchymal …

The development of new therapeutic approaches to treat type 1 diabetes mellitus (T1D)
relies on the precise understanding and deciphering of insulin-secreting β-cell biology, as …

Diabetes Mellitus is a group of diseases characterized by high blood glucose levels due to
patients' inability to produce sufficient insulin. Current interventions often require implants …

The promise of cell therapy has been augmented by introducing biomaterials, where
intricate scaffold shapes are fabricated to accommodate the cells within. In this review, we …

Type 1 Diabetes Mellitus (T1DM) is characterized by the autoimmune destruction of β-cells
in the pancreatic islets. In this regard, islet transplantation aims for the replacement of the …