Background Pharmacotherapy provides an option for adults with overweight and obesity to
reduce their bodyweight if lifestyle modifications fail. We summarised the latest evidence for …

Objective To evaluate sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-
like peptide-1 (GLP-1) receptor agonists in patients with type 2 diabetes at varying …

Network meta-analysis compares different interventions for the same condition, by
combining direct and indirect evidence derived from all eligible studies. Network …

Doing Meta-Analysis with R: A Hands-On Guide serves as an accessible introduction on
how meta-analyses can be conducted in R. Essential steps for meta-analysis are covered …

Background Many psychosocial and psychological interventions are used in patients with
schizophrenia, but their comparative efficacy in the prevention of relapse is not known. We …

Objective To assess the effectiveness and safety of different preparations and doses of non-
steroidal anti-inflammatory drugs (NSAIDs), opioids, and paracetamol for knee and hip …

Background Schizophrenia is a common, severe, and usually chronic disorder. Maintenance
treatment with antipsychotic drugs can prevent relapse but also causes side-effects. We …

Question What are the effects of specific types of exercise treatments on pain intensity and
functional limitation outcomes for adults with chronic low back pain? Design Systematic …

Background Schizophrenia is one of the most common, burdensome, and costly psychiatric
disorders in adults worldwide. Antipsychotic drugs are its treatment of choice, but there is …

Objective To assess the associations between statins and adverse events in primary
prevention of cardiovascular disease and to examine how the associations vary by type and …