Structural modeling using solution small-angle X-ray scattering (SAXS)

TW Gräwert, DI Svergun - Journal of molecular biology, 2020 - Elsevier
Small-angle X-ray scattering (SAXS) offers a way to examine the overall shape and
oligomerization state of biological macromolecules under quasi native conditions in solution …

[PDF][PDF] ATSAS 3.0: expanded functionality and new tools for small-angle scattering data analysis

K Manalastas-Cantos, PV Konarev… - Journal of applied …, 2021 - journals.iucr.org
The ATSAS software suite encompasses a number of programs for the processing,
visualization, analysis and modelling of small-angle scattering data, with a focus on the data …

[HTML][HTML] ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

D Franke, MV Petoukhov, PV Konarev… - Journal of applied …, 2017 - scripts.iucr.org
ATSAS is a comprehensive software suite for the analysis of small-angle scattering data
from dilute solutions of biological macromolecules or nanoparticles. It contains applications …

[PDF][PDF] BioXTAS RAW: improvements to a free open-source program for small-angle X-ray scattering data reduction and analysis

JB Hopkins, RE Gillilan, S Skou - Journal of applied crystallography, 2017 - journals.iucr.org
BioXTAS RAW is a graphical-user-interface-based free open-source Python program for
reduction and analysis of small-angle X-ray solution scattering (SAXS) data. The software is …

Recent advances in small-angle scattering and its expanding impact in structural biology

J Trewhella - Structure, 2022 - cell.com
Applications of small-angle scattering (SAS) in structural biology have benefited from
continuing developments in instrumentation, tools for data analysis, modeling capabilities …

[PDF][PDF] 2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update

J Trewhella, AP Duff, D Durand, F Gabel… - … Section D: Structural …, 2017 - journals.iucr.org
In 2012, preliminary guidelines were published addressing sample quality, data acquisition
and reduction, presentation of scattering data and validation, and modelling for biomolecular …

Consensus Bayesian assessment of protein molecular mass from solution X-ray scattering data

NR Hajizadeh, D Franke, CM Jeffries, DI Svergun - Scientific reports, 2018 - nature.com
Molecular mass (MM) is one of the key structural parameters obtained by small-angle X-ray
scattering (SAXS) of proteins in solution and is used to assess the sample quality, oligomeric …

Dynamic light scattering (DLS) principles, perspectives, applications to biological samples

S Falke, C Betzel - Radiation in bioanalysis: Spectroscopic techniques …, 2019 - Springer
Focus a laser on dissolved particles and analyze the scattered light to reveal their size. This
well established principle is used in dynamic light scattering (DLS), or also called photon …

Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments

CM Jeffries, MA Graewert, CE Blanchet, DB Langley… - Nature protocols, 2016 - nature.com
Small-angle X-ray scattering (SAXS) and small-angle neutron scattering (SANS) are
techniques used to extract structural parameters and determine the overall structures and …

Structure and activation of C1, the complex initiating the classical pathway of the complement cascade

SA Mortensen, B Sander, RK Jensen… - Proceedings of the …, 2017 - National Acad Sciences
The complement system is an important antimicrobial and inflammation-generating
component of the innate immune system. The classical pathway of complement is activated …