COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

COVID-19 vaccination: The road ahead

DM Altmann, RJ Boyton - Science, 2022 - science.org
A diverse array of successful, first-generation SARS-CoV-2 vaccines have played a huge
role in efforts to bring the COVID-19 pandemic under control, even though inequitable …

Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection

A Zhang, HD Stacey, MR D'Agostino, Y Tugg… - Nature Reviews …, 2023 - nature.com
Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …

COVID-19 vaccine development: milestones, lessons and prospects

M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …

Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia

A Greinacher, K Selleng, R Palankar… - Blood, The Journal …, 2021 - ashpublications.org
Abstract SARS-CoV-2 vaccine ChAdOx1 nCoV-19 (AstraZeneca) causes a thromboembolic
complication termed vaccine-induced immune thrombotic thrombocytopenia (VITT). Using …

Adenovirus-associated thrombocytopenia, thrombosis, and VITT-like antibodies

TE Warkentin, J Baskin-Miller… - … England Journal of …, 2023 - Mass Medical Soc
Thrombosis and Thrombocytopenia from Adenovirus Infection VITT is caused by antibodies
to PF4 that recognize the heparin-binding site. Thrombocytopenia and thrombosis …

Characterization of nanoparticles-based vaccines for COVID-19

G Guerrini, D Magrì, S Gioria, D Medaglini… - Nature …, 2022 - nature.com
Several vaccines against COVID-19 use nanoparticles to protect the antigen cargo (either
proteins or nucleic acids), increase the immunogenicity and ultimately the efficacy. The …

Vaccine-induced immune thrombotic thrombocytopenia

FA Klok, M Pai, MV Huisman, M Makris - The Lancet Haematology, 2022 - thelancet.com
In response to the COVID-19 pandemic, vaccines for SARS-CoV-2 were developed, tested,
and introduced at a remarkable speed. Although the vaccine introduction had a major …

Case series of thrombosis with thrombocytopenia syndrome after COVID-19 vaccination—United States, December 2020 to August 2021

I See, A Lale, P Marquez, MB Streiff… - Annals of internal …, 2022 - acpjournals.org
Background: Thrombosis with thrombocytopenia syndrome (TTS) is a potentially life-
threatening condition associated with adenoviral-vectored COVID-19 vaccination. It presents …

Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus …

JG Rizk, A Gupta, P Sardar, BM Henry… - JAMA …, 2021 - jamanetwork.com
Importance The COVID-19 pandemic saw one of the fastest developments of vaccines in an
effort to combat an out-of-control pandemic. The 2 most common COVID-19 vaccine …