The history of antiretroviral therapy and of its implementation in resource-limited areas of the world
HIV/AIDS not only represents the most severe epidemic in modern times, but also the
greatest public health challenge in history. The response of the scientific community has …
greatest public health challenge in history. The response of the scientific community has …
Resistance to enfuvirtide, the first HIV fusion inhibitor
ML Greenberg, N Cammack - Journal of Antimicrobial …, 2004 - academic.oup.com
Fusion inhibitors are a new class of antiretroviral drugs (ARVs) for the treatment of human
immunodeficiency virus infection. Enfuvirtide is the first in this class to reach market …
immunodeficiency virus infection. Enfuvirtide is the first in this class to reach market …
[HTML][HTML] Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies
Antiretroviral Therapy Cohort Collaboration - The Lancet, 2008 - Elsevier
BACKGROUND: Combination antiretroviral therapy has led to significant increases in
survival and quality of life, but at a population-level the effect on life expectancy is not well …
survival and quality of life, but at a population-level the effect on life expectancy is not well …
[图书][B] Antiretroviral therapy for HIV infection in adults and adolescents: recommendations for a public health approach-2010 revision
World Health Organization - 2010 - apps.who.int
ISBN 978 92 4 459976 1(NLM classification: WC 503.2)© всемирная организация
здравоохранения, 2010 г. все права защищены. публикации всемирной организации …
здравоохранения, 2010 г. все права защищены. публикации всемирной организации …
Sex differences in the Toll-like receptor–mediated response of plasmacytoid dendritic cells to HIV-1
A Meier, JJ Chang, ES Chan, RB Pollard, HK Sidhu… - Nature medicine, 2009 - nature.com
Manifestations of viral infections can differ between women and men, and marked sex
differences have been described in the course of HIV-1 disease. HIV-1–infected women …
differences have been described in the course of HIV-1 disease. HIV-1–infected women …
Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV
JE Gallant, E DeJesus, JR Arribas… - … England Journal of …, 2006 - Mass Medical Soc
Background Durable suppression of replication of the human immunodeficiency virus (HIV)
depends on the use of potent, well-tolerated antiretroviral regimens to which patients can …
depends on the use of potent, well-tolerated antiretroviral regimens to which patients can …
Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society–USA panel
SM Hammer, MS Saag, M Schechter, JSG Montaner… - Jama, 2006 - jamanetwork.com
ContextGuidelines for antiretroviral therapy are important for clinicians worldwide given the
complexity of the field and the varied clinical situations in which these agents are used. The …
complexity of the field and the varied clinical situations in which these agents are used. The …
Efficacy and safety of TMC125 (etravirine) in treatment-experienced HIV-1-infected patients in DUET-2: 24-week results from a randomised, double-blind, placebo …
A Lazzarin, T Campbell, B Clotet, M Johnson… - The Lancet, 2007 - thelancet.com
Background TMC125 (etravirine) is a non-nucleoside reverse-transcriptase inhibitor
(NNRTI) with activity against NNRTI-resistant HIV-1 in phase IIb trials. The aim of DUET-2 is …
(NNRTI) with activity against NNRTI-resistant HIV-1 in phase IIb trials. The aim of DUET-2 is …
Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection
ContextPlasma human immunodeficiency virus (HIV) RNA level predicts HIV disease
progression, but the extent to which it explains the variability in rate of CD4 cell depletion is …
progression, but the extent to which it explains the variability in rate of CD4 cell depletion is …
The prevalence of antiretroviral drug resistance in the United States
DD Richman, SC Morton, T Wrin, N Hellmann, S Berry… - Aids, 2004 - journals.lww.com
Background: Antiretroviral therapy has dramatically reduced the morbidity and mortality of
infection due to HIV. The emergence of drug-resistant virus has limited the usefulness of …
infection due to HIV. The emergence of drug-resistant virus has limited the usefulness of …