Dengue: update on clinically relevant therapeutic strategies and vaccines

M Palanichamy Kala, AL St. John… - Current Treatment Options …, 2023 - Springer
Opinion statement Dengue viruses (DENV) continue to circulate worldwide, resulting in a
significant burden on human health. There are four antigenically distinct serotypes of DENV …

Viral emerging diseases: challenges in developing vaccination strategies

M Trovato, R Sartorius, L D'Apice, R Manco… - Frontiers in …, 2020 - frontiersin.org
In the last decades, a number of infectious viruses have emerged from wildlife or re-
emerged, generating serious threats to the global health and to the economy worldwide …

Potential antigenic cross-reactivity between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and dengue viruses

Y Lustig, S Keler, R Kolodny, N Ben-Tal… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) and dengue fever are difficult
to distinguish given shared clinical and laboratory features. Failing to consider COVID-19 …

A prospective observational safety study on ChAdOx1 nCoV-19 corona virus vaccine (recombinant) use in healthcare workers-first results from India

U Kaur, B Ojha, BK Pathak, A Singh, KR Giri… - …, 2021 - thelancet.com
Background We provide the first post-approval safety analysis of COVISHIELD in health care
workers (HCWs) in northern India. Methods This continuing prospective observational study …

Serological cross-reactivity among common flaviviruses

KR Chan, AA Ismail, G Thergarajan, CS Raju… - Frontiers in Cellular …, 2022 - frontiersin.org
The Flavivirus genus is made up of viruses that are either mosquito-borne or tick-borne and
other viruses transmitted by unknown vectors. Flaviviruses present a significant threat to …

Diagnostic approach for arboviral infections in the United States

A Piantadosi, S Kanjilal - Journal of clinical microbiology, 2020 - Am Soc Microbiol
Domestic arthropod-borne viruses (arboviruses) are single-stranded RNA viruses, the most
common of which include the mosquito-borne West Nile virus, St. Louis encephalitis virus …

Exacerbated Zika virus–induced neuropathology and microcephaly in fetuses of dengue-immune nonhuman primates

WAA Saron, K Shanmugam, CC Tung… - Science Translational …, 2023 - science.org
Zika virus (ZIKV) is a mosquito-borne flavivirus that can vertically transmit from mother to
fetus, potentially causing congenital defects, including microcephaly. It is not fully …

[HTML][HTML] Next-generation diagnostic test for dengue virus detection using an ultrafast plasmonic colorimetric RT-PCR strategy

K Jiang, JH Lee, TS Fung, J Wu, C Liu, H Mi… - Analytica chimica …, 2023 - Elsevier
The current global COVID-19 pandemic once again highlighted the urgent need for a
simple, cost-effective, and sensitive diagnostic platform that can be rapidly developed for …

The role of NS1 protein in the diagnosis of flavivirus infections

R Fisher, Y Lustig, EH Sklan, E Schwartz - Viruses, 2023 - mdpi.com
Nonstructural protein 1 (NS1) is a glycoprotein among the flavivirus genus. It is found in both
membrane-associated and soluble secreted forms, has an essential role in viral replication …

Antibody dependent enhancement: Unavoidable problems in vaccine development

L Xu, Z Ma, Y Li, Z Pang, S Xiao - Advances in immunology, 2021 - Elsevier
In some cases, antibodies can enhance virus entry and replication in cells. This
phenomenon is called antibody-dependent infection enhancement (ADE). ADE not only …