[HTML][HTML] Current treatment options and the role of peptides as potential therapeutic components for Middle East Respiratory Syndrome (MERS): a review

S Mustafa, H Balkhy, MN Gabere - Journal of infection and public health, 2018 - Elsevier
Abstract Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a highly
pathogenic respiratory virus with mechanisms that may be driven by innate immune …

Advancements in peptide-based antimicrobials: A possible option for emerging drug-resistant infections

N Yadav, VS Chauhan - Advances in Colloid and Interface Science, 2024 - Elsevier
In recent years, multidrug-resistant pathogenic microorganisms (MDROs) have emerged as
a severe threat to human health, exhibiting robust resistance to traditional antibiotics. This …

Empirical comparison of web-based antimicrobial peptide prediction tools

MN Gabere, WS Noble - Bioinformatics, 2017 - academic.oup.com
Abstract Motivation Antimicrobial peptides (AMPs) are innate immune molecules that exhibit
activities against a range of microbes, including bacteria, fungi, viruses and protozoa …

Plant antimicrobial peptides (PAMPs): features, applications, production, expression, and challenges

OO Bakare, A Gokul, AO Fadaka, R Wu, LA Niekerk… - Molecules, 2022 - mdpi.com
The quest for an extraordinary array of defense strategies is imperative to reduce the
challenges of microbial attacks on plants and animals. Plant antimicrobial peptides (PAMPs) …

Biomedical relevance of novel anticancer peptides in the sensitive treatment of cancer

OO Bakare, A Gokul, R Wu, LA Niekerk, A Klein… - Biomolecules, 2021 - mdpi.com
The global increase in cancer mortality and economic losses necessitates the cautious
quest for therapeutic agents with compensatory advantages over conventional therapies …

Middle East respiratory syndrome: pathogenesis and therapeutic developments

H Choudhry, MA Bakhrebah, WH Abdulaal… - Future …, 2019 - Taylor & Francis
The first case of Middle East respiratory syndrome coronavirus (MERS-CoV) was identified
in the year 2012, which spread rapidly and increased to more than 2200 in 2018. This highly …

Antibacterial activity of rationally designed antimicrobial peptides

MB Tincho, T Morris, M Meyer… - International Journal of …, 2020 - Wiley Online Library
Many infectious diseases are still prevalent in the world's populations since no effective
treatments are available to eradicate them. The reasons may either be the antibiotic …

[HTML][HTML] In silico prediction of new antimicrobial peptides and proteins as druggable targets towards alternative anti-schistosomal therapy

RT Aruleba, MB Tincho, A Pretorius, AP Kappo - Scientific African, 2021 - Elsevier
Schistosomiasis is a debilitating disease caused by a parasitic flatworm found in freshwater.
With the exponential increase in prevalence, Praziquantel (PZQ) remains the only effective …

Dietary effects of antimicrobial peptides in therapeutics

OO Bakare, AO Fadaka, A Klein, A Pretorius - All Life, 2020 - Taylor & Francis
The notable increase in drug-resistant infections and the failure of the most potent antibiotics
to establish their curative effect without side effect have presented a serious need for the …

Structural and molecular docking analytical studies of the predicted ligand binding sites of cadherin-1 in cancer prognostics

OO Bakare, AO Fadaka, M Keyster… - … and Applications in …, 2020 - Taylor & Francis
Introduction Several studies have explored the design of antimicrobial peptides (AMPs) for
the development of therapeutic and diagnostic molecules for the treatment and identification …