Platinum-based anticancer drugs, including cisplatin, carboplatin, oxaliplatin, nedaplatin,
and lobaplatin, are heavily applied in chemotherapy regimens. However, the intrinsic or …

The ability to efficiently deliver a drug to a tumor site is dependent on a wide range of
physiologically imposed design constraints. Nanotechnology provides the possibility of …

Cancer is one of the leading causes of death globally. The development of drug resistance
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …

Recent research has examined Akt and Akt-related serine–threonine kinases in signaling
cascades that regulate cell survival and are important in the pathogenesis of degenerative …

Apoptosis, or programmed cell death, has an essential role in controlling cell number in
many developmental and physiological settings and in chemotherapy-induced tumour-cell …

Dramatic changes in the structure of cell membranes on apoptosis allow easy, sensitive and
non-destructive analysis of this process with the application of fluorescence methods. The …

Adverse effects are pressing challenges produced by chemotherapy and radiotherapy for
the treatment of breast cancer. Nontoxic herbal medicines are therefore considered as a …

Phytochemicals are recognized as playing an important role in cancer prevention by fruits
and vegetables. The avocado is a widely grown and consumed fruit that is high in nutrients …

Platinum‐based compounds are widely used as chemotherapeutics for the treatment of a
variety of cancers. The anticancer activity of cisplatin and other platinum drugs is believed to …

Over the past two decades, the role of apoptosis in the cytotoxicity of anticancer drugs has
become clear. Apoptosis may occur via a death receptor‐dependent (extrinsic) or …