Terminally Exhausted CD8+ T Cells Resistant to PD-1 Blockade Promote Generation and Maintenance of Aggressive Cancer Stem Cells
M Chakravarti, S Dhar, S Bera, A Sinha, K Roy… - Cancer research, 2023 - AACR
Heterogeneity within the tumor-infiltrating lymphocytes (TIL) population limits
immunotherapeutic efficacy against cancer. Between two subpopulations of exhausted …
immunotherapeutic efficacy against cancer. Between two subpopulations of exhausted …
Akt/mTOR Activation in Lung Cancer Tumorigenic Regulators and Their Potential Value as Biomarkers
C Sousa, B Silva-Lima, M Videira - Onco, 2022 - mdpi.com
Simple Summary Key breakthroughs in evidence gathered from genetic and epigenetic data
from lung cancer patient samples are related to dissimilar levels of gene expression both in …
from lung cancer patient samples are related to dissimilar levels of gene expression both in …
PLEK2 mediates metastasis and invasion via α5‐nAChR activation in nicotine‐induced lung adenocarcinoma
Q Li, J Li, J Wang, J Wang, T Lu, Y Jia… - Molecular …, 2024 - Wiley Online Library
Evidence has shown a strong relationship between smoking and epithelial mesenchymal
transition (EMT). α5‐nicotinic acetylcholine receptor (α5‐nAChR) contributes to nicotine …
transition (EMT). α5‐nicotinic acetylcholine receptor (α5‐nAChR) contributes to nicotine …
E2F4-induced AGAP2-AS1 up-regulation accelerates the progression of colorectal cancer via miR-182-5p/CFL1 axis
Z Guo, X Liu, H Shao - Digestive and Liver Disease, 2022 - Elsevier
Abstract Background Long non-coding RNAs (lncRNAs) are closely associated with the
pathogenesis of numerous diseases including cancers. LncRNA AGAP2 Antisense RNA 1 …
pathogenesis of numerous diseases including cancers. LncRNA AGAP2 Antisense RNA 1 …
Cofilin1 Is a Poorer Prognostic Biomarker and potential Immunotherapy in Systematic Pan-Cancer
J Yang, CJ Qiu, S Zhong, Y Xiang, SJ Pan - 2022 - researchsquare.com
Background: Cofilin1 (CFL1) is an actin-binding protein that can impact the prognosis of
patients with malignant cancer through different mechanisms. However, the CFL1 and pan …
patients with malignant cancer through different mechanisms. However, the CFL1 and pan …