H Maiato, J DeLuca, ED Salmon… - Journal of cell …, 2004 - journals.biologists.com
The kinetochore is a control module that both powers and regulates chromosome segregation in mitosis and meiosis. The kinetochore-microtubule interface is remarkably …
A Harel, DJ Forbes - Molecular cell, 2004 - cell.com
Importin β, once thought to be exclusively a nuclear transport receptor, is emerging as a global regulator of diverse cellular functions. Importin β acts positively in multiple interphase …
RanGAP1 was the first documented substrate for conjugation with the ubiquitin-like protein SUMO-1. However, the functional significance of this conjugation has not been fully clarified …
A Harel, AV Orjalo, T Vincent, A Lachish-Zalait, S Vasu… - Molecular cell, 2003 - cell.com
The vertebrate nuclear pore complex, 30 times the size of a ribosome, assembles from a library of soluble subunits and two membrane proteins. Using immunodepletion of Xenopus …
Ran is a member of the Ras superfamily of proteins, which primarily regulates nucleocytoplasmic trafficking and mediates mitosis by regulating spindle formation and …
SK Vasu, DJ Forbes - Current opinion in cell biology, 2001 - Elsevier
Communication between the nucleus and cytoplasm occurs through large macromolecular structures, the nuclear pores. Quantitative scanning transmission electron microscopy has …
CPC De Souza, AH Osmani, SB Hashmi, SA Osmani - Current biology, 2004 - cell.com
Background: Many organisms undergo closed mitosis and locate tubulin and mitotic kinases to nuclei only during mitosis. How this is regulated is unknown. Interestingly, the NIMA …
E Nielsen - Annual Review of Plant Biology, 2020 - annualreviews.org
Small GTP-binding proteins represent a highly conserved signaling module in eukaryotes that regulates diverse cellular processes such as signal transduction, cytoskeletal …
S Song, W Cong, S Zhou, Y Shi, W Dai, H Zhang… - Asian journal of …, 2019 - Elsevier
Small GTPase is a kind of GTP-binding protein commonly found in eukaryotic cells. It plays an important role in cytoskeletal reorganization, cell polarity, cell cycle progression, gene …