Polycystic ovary syndrome

AE Joham, RJ Norman, E Stener-Victorin… - The lancet Diabetes & …, 2022 - thelancet.com
Polycystic ovary syndrome (PCOS) affects 5–18% of women, and is a reproductive,
metabolic, and psychological condition with impacts across the lifespan. The cause is …

Insulin resistance in polycystic ovary syndrome across various tissues: an updated review of pathogenesis, evaluation, and treatment

H Zhao, J Zhang, X Cheng, X Nie, B He - Journal of Ovarian Research, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by
chronic ovulation dysfunction and overabundance of androgens; it affects 6–20% of women …

Deconstructing a syndrome: genomic insights into PCOS causal mechanisms and classification

M Dapas, A Dunaif - Endocrine reviews, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is among the most common disorders in women of
reproductive age, affecting up to 15% worldwide, depending on the diagnostic criteria …

The impact of the gut microbiota on the reproductive and metabolic endocrine system

X Qi, C Yun, Y Pang, J Qiao - Gut microbes, 2021 - Taylor & Francis
As the gut microbiota exerts various effects on the intestinal milieu which influences distant
organs and pathways, it is considered to be a full-fledged endocrine organ. The microbiota …

Polycystic ovary syndrome: pathophysiology, presentation, and treatment with emphasis on adolescent girls

SF Witchel, SE Oberfield, AS Peña - Journal of the Endocrine …, 2019 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a heterogeneous disorder characterized by
hyperandrogenism and chronic anovulation. Depending on diagnostic criteria, 6% to 20% of …

Epigenetic inheritance of polycystic ovary syndrome—challenges and opportunities for treatment

E Stener-Victorin, Q Deng - Nature Reviews Endocrinology, 2021 - nature.com
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and is
associated with a substantially increased lifetime risk of comorbidities, including type 2 …

Insulin resistance and PCOS: chicken or egg?

P Moghetti, F Tosi - Journal of endocrinological investigation, 2021 - Springer
PCOS is a common and heterogeneous endocrine disorder in women of reproductive age,
frequently associated with metabolic abnormalities. It was estimated that about 75% of these …

Modulation of the inflammatory response in polycystic ovary syndrome (PCOS)—searching for epigenetic factors

D Szukiewicz, S Trojanowski, A Kociszewska… - International journal of …, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age. Despite its incidence, the syndrome is poorly understood and remains …

Multi-system reproductive metabolic disorder: significance for the pathogenesis and therapy of polycystic ovary syndrome (PCOS)

Y Li, C Chen, Y Ma, J Xiao, G Luo, Y Li, D Wu - Life sciences, 2019 - Elsevier
Polycystic ovary syndrome (PCOS), a multisystem disease, is a major reason for female
infertility around the world. It is no longer considered simply as a disease of ovary. Now …

A “one‐stop shop” decision tree for diagnosing and phenotyping polycystic ovarian syndrome on serum metabolic fingerprints

R Wang, Z Gu, Y Wang, X Yin, W Liu… - Advanced Functional …, 2022 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is a common endocrine disease regulated by metabolic
disorders, the effective intervention of which depends on diverse phenotypes (eg, insulin …