Type 1 diabetes affects millions of people globally and requires careful management to
avoid serious long-term complications, including heart and kidney disease, stroke, and loss …

Although plenty of drugs are currently available for type 2 diabetes mellitus (T2DM), a subset
of patients still failed to restore normoglycemia. Recent studies proved that symptoms of …

Stem-cell-based therapies can potentially reverse organ dysfunction and diseases, but the
removal of impaired tissue and activation of a program leading to organ regeneration pose …

The islets of Langerhans or pancreatic islets are pivotal in the control of blood glucose and
are complex microorgans embedded within the larger volume of the exocrine pancreas …

Mesenchymal stem cells are the most widely used cell phenotype for therapeutic
applications, the main reasons being their well-established abilities to promote regeneration …

Cellular therapies offer novel opportunities for the treatment of type 2 diabetes mellitus
(T2DM). The present study evaluated the long-term efficacy and safety of infusion of …

Background Type 2 diabetes mellitus (T2DM) is a serious threat to human health and
remains incurable. Insulin deficiency seems to be attributed to the progressive failure of …

Background Mesenchymal stem cells (MSC) are non-haematopoietic, fibroblast-like
multipotent stromal cells. In the injured pancreas, these cells are assumed to secrete growth …

Diabetic retinopathy (DR) is a multifactorial microvascular disease induced by
hyperglycemia and subsequent metabolic abnormalities. The resulting cell stress causes a …

Type 1 diabetes mellitus is an autoimmune disease resulting from the destruction of insulin-
producing pancreatic β-cells. Cell-based therapies, involving the transplantation of …