[PDF][PDF] Interactions and incompatibilities of pharmaceutical excipients with active pharmaceutical ingredients: a comprehensive review

SS Bharate, SB Bharate… - International Journal of …, 2016 - jefc.scholasticahq.com
Studies of active drug/excipient compatibility represent an important phase in the
preformulation stage of the development of all dosage forms. The potential physical and …

Análise térmica aplicada a fármacos e formulações farmacêuticas na indústria farmacêutica

MA Oliveira, MI Yoshida, EC Lima Gomes - Química Nova, 2011 - SciELO Brasil
Several matters of the pharmaceutical demonstrate the great importance of thermal analysis
application, especially TG and DSC for the pharmaceutical industry future, namely …

A 3D printed bilayer oral solid dosage form combining metformin for prolonged and glimepiride for immediate drug delivery

CI Gioumouxouzis, A Baklavaridis… - European Journal of …, 2018 - Elsevier
Abstract Fused Deposition Modelling (aka FDM-3D printing) has been previously employed
in the development of personalized medicines with unique properties and release behavior …

Skin Delivery and in Vitro Biological Evaluation of Trans-Resveratrol-Loaded Solid Lipid Nanoparticles for Skin Disorder Therapies

RB Rigon, N Fachinetti, P Severino, MHA Santana… - Molecules, 2016 - mdpi.com
The aim of this study was to evaluate the skin delivery and in vitro biological activity of trans-
resveratrol (RES)-loaded solid lipid nanoparticles (SLNs). The SLNs were composed of …

Study of thermal behavior of phytic acid

ALM Daneluti, JR Matos - Brazilian Journal of Pharmaceutical …, 2013 - SciELO Brasil
Phytic acid is a natural compound widely used as depigmenting agent in galenic cosmetic
emulsions. However, we have observed experimentally that phytic acid, when heated to 150 …

Investigation of the heating rate dependency associated with the loss of crystalline structure in sucrose, glucose, and fructose using a thermal analysis approach (part I …

JW Lee, LC Thomas, SJ Schmidt - Journal of agricultural and food …, 2011 - ACS Publications
Thermodynamic melting occurs at a single, time-independent temperature with a constant
enthalpy value. However, substantial variation in the melting parameters (T m onset, T m …

Nanostructured lipid carriers for incorporation of copper(II) complexes to be used against Mycobacterium tuberculosis

MR Sato, JA Oshiro Junior, RTA Machado… - Drug design …, 2017 - Taylor & Francis
Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis. Cessation of
treatment before the recommended conclusion may lead to the emergence of multidrug …

[HTML][HTML] Thermal behavior and decomposition kinetics of rifampicin polymorphs under isothermal and non-isothermal conditions

R Alves, TVS Reis, LCC Silva, S Storpírtis… - Brazilian Journal of …, 2010 - SciELO Brasil
The thermal behavior of two polymorphic forms of rifampicin was studied by DSC and
TG/DTG. The thermoanalytical results clearly showed the differences between the two …

Synthesis of pyrazolone derivatives and their nanometer Ag (I) complexes and physicochemical, DNA binding, antitumor, and theoretical implementations

I Althagafi, NM El-Metwaly… - Bioinorganic …, 2018 - Wiley Online Library
Four pyrazolone derivatives and their corresponding silver complexes were synthesized and
characterized. Based on elemental analysis, 1: 2 (M: L) molar ratio was suggested for all …

Application of thermal analysis to the study of antituberculosis drugs–excipient compatibility

EP Lavor, MVM Navarro, FD Freire, CFS Aragão… - Journal of Thermal …, 2014 - Springer
First-line drugs (rifampicin, RIF; isoniazid, INH; ethambutol, ETA; and pyrazinamide, PZA)
recommended in conventional treatment of tuberculosis were analyzed in 1: 1 w/w binary …