Objectives To review systematically the evidence of age-related macular degeneration (AMD) affecting real-world visual ability and quality of life (QoL). To explore trends in specific …
M Tamhane, S Cabrera-Ghayouri, G Abelian… - Pharmaceutical …, 2019 - Springer
Biomarkers provide a powerful and dynamic approach to improve our understanding of the mechanisms underlying ocular diseases with applications in diagnosis, disease modulation …
AW Stitt, N Lois, RJ Medina, P Adamson… - Clinical …, 2013 - portlandpress.com
Diabetic retinopathy remains the most common complication of diabetes mellitus and is a leading cause of visual loss in industrialized nations. The clinicopathology of the diabetic …
X Wang, T Wang, E Lam, D Alvarez, Y Sun - International Journal of …, 2023 - mdpi.com
The eye is an immune privileged tissue that insulates the visual system from local and systemic immune provocation to preserve homeostatic functions of highly specialized retinal …
J Figueira, E Fletcher, P Massin, R Silva, F Bandello… - Ophthalmology, 2018 - Elsevier
Purpose Comparison of the efficacy of ranibizumab (RBZ) 0.5 mg intravitreal injections plus panretinal photocoagulation (PRP) versus PRP alone in the regression of the …
C Raimondi, A Fantin, A Lampropoulou… - Journal of Experimental …, 2014 - rupress.org
To enable new blood vessel growth, endothelial cells (ECs) express neuropilin 1 (NRP1), and NRP1 associates with the receptor tyrosine kinase VEGFR2 after binding the vascular …
B Rajesh, J Zarranz-Ventura, AT Fung… - British Journal of …, 2020 - bjo.bmj.com
Purpose To evaluate the real-life safety profile of intravitreal dexamethasone implant injection for various retinal conditions. Methods Retrospective multicenter analysis of …
DY Chen, NH Sun, X Chen, JJ Gong… - The Journal of …, 2021 - Am Soc Clin Investig
Abnormal angiogenesis and regression of the diseased retinal vasculature are key processes associated with ischemic retinopathies, but the underlying mechanisms that …
W Liu, BS Lee, WF Mieler, JJ Kang-Mieler - Current eye research, 2019 - Taylor & Francis
Purpose: Current standard of care for neovascular eye diseases require repeated intravitreal bolus injections of anti-vascular endothelial growth factors (anti-VEGFs). The purpose of this …