Resident tissue macrophages: Key coordinators of tissue homeostasis beyond immunity

J Zhao, I Andreev, HM Silva - Science Immunology, 2024 - science.org
Resident tissue macrophages (RTMs) encompass a highly diverse set of cells abundantly
present in every tissue and organ. RTMs are recognized as central players in innate immune …

Understanding testicular single cell transcriptional atlas: from developmental complications to male infertility

MB Tirumalasetty, I Bhattacharya… - Frontiers in …, 2024 - frontiersin.org
Spermatogenesis is a multi-step biological process where mitotically active diploid (2n)
spermatogonia differentiate into haploid (n) spermatozoa via regulated meiotic …

Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia …

K Zec, S Thiebes, J Bottek, D Siemes… - Frontiers in …, 2023 - frontiersin.org
Introduction Streptococcus pneumoniae is one of the main causes of community-acquired
infections in the lung alveoli in children and the elderly. Alveolar macrophages (AM) patrol …

Macrophages of multiple hematopoietic origins reside in the developing prostate

SW Feng, TM North, P Wivell, A Pletcher… - …, 2024 - journals.biologists.com
Tissue-resident macrophages contribute to the organogenesis of many tissues. Growth of
the prostate is regulated by androgens during puberty, yet androgens are considered …

[HTML][HTML] Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance

H Lehtonen, H Jokela, J Hofmann, L Tola, A Mehmood… - Cell Reports, 2025 - Elsevier
The pituitary gland is the central endocrine regulatory organ producing and releasing
hormones that coordinate major body functions. The physical location of the pituitary gland …

Role of macrophage colony stimulating factor and interferon regulatory factor 7 in modulating the immune profile of mouse testicular macrophages

Y Yang, V Kumar, W Peng, M Fijak, M Gabriela… - Journal of Reproductive …, 2024 - Elsevier
Testicular macrophages (TM) are critical for the function of the testis by regulating
homeostasis and inflammatory responses. However, the mechanisms by which TM fulfil …

Testicular immunity

SY Li, S Kumar, X Gu, T DeFalco - Molecular Aspects of Medicine, 2024 - Elsevier
The testis is a unique environment where immune responses are suppressed to allow the
development of sperm that possess autoimmunogenic antigens. There are several …

Fate‐mapping studies in inbred mice: A model for understanding macrophage development and homeostasis?

DA Hume - European Journal of Immunology, 2023 - Wiley Online Library
The mononuclear phagocyte system (MPS) was defined in the early 1970s as a family of
cells including progenitors, monocytes in the circulation, and resident tissue macrophages …

Size-dependent deleterious effects of nano-and microplastics on sperm motility

Z Lin, Z Li, S Ji, HS Lo, B Billah, A Sharmin, X Han… - Toxicology, 2024 - Elsevier
Introduction Growing concerns regarding the reproductive toxicity associated with daily life
exposure to micro-/nano-plastics (abbreviated as MNPs) have become increasingly …

Beyond defence: Immune architects of ovarian health and disease

MV Bazzano, A Köninger, ME Solano - Seminars in Immunopathology, 2024 - Springer
Throughout the individual's reproductive period of life the ovary undergoes continues
changes, including cyclic processes of cell death, tissue regeneration, proliferation, and …