The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance, and therapeutic implications
In some patients with major depressive disorder (MDD), individual illness characteristics
appear consistent with those of a neuroprogressive illness. Features of neuroprogression …
appear consistent with those of a neuroprogressive illness. Features of neuroprogression …
Understanding heterogeneity in grey matter research of adults with childhood maltreatment—A meta-analysis and review
C Paquola, MR Bennett, J Lagopoulos - Neuroscience & Biobehavioral …, 2016 - Elsevier
Childhood trauma has been associated with long term effects on prefrontal-limbic grey
matter. A literature search was conducted to identify structural magnetic resonance imaging …
matter. A literature search was conducted to identify structural magnetic resonance imaging …
Anatomy of bipolar disorder and schizophrenia: a meta-analysis
I Ellison-Wright, ED Bullmore - Schizophrenia research, 2010 - Elsevier
BACKGROUND: Recent genetic results have indicated that the two major, classically distinct
forms of psychosis–schizophrenia and bipolar disorder–may share causative factors in …
forms of psychosis–schizophrenia and bipolar disorder–may share causative factors in …
Personalized medicine in psychiatry: problems and promises
U Ozomaro, C Wahlestedt, CB Nemeroff - BMC medicine, 2013 - Springer
The central theme of personalized medicine is the premise that an individual's unique
physiologic characteristics play a significant role in both disease vulnerability and in …
physiologic characteristics play a significant role in both disease vulnerability and in …
Voxelwise meta-analysis of gray matter abnormalities in bipolar disorder
BACKGROUND: We conducted a meta-analysis of gray matter abnormalities in bipolar
disorder (BD) using voxel-based morphometry studies to help clarify the structural …
disorder (BD) using voxel-based morphometry studies to help clarify the structural …
Using structural MRI to identify bipolar disorders–13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group
Bipolar disorders (BDs) are among the leading causes of morbidity and disability. Objective
biological markers, such as those based on brain imaging, could aid in clinical management …
biological markers, such as those based on brain imaging, could aid in clinical management …
Excess significance bias in the literature on brain volume abnormalities
JPA Ioannidis - Archives of general psychiatry, 2011 - jamanetwork.com
Context Many studies report volume abnormalities in diverse brain structures in patients with
various mental health conditions. Objective To evaluate whether there is evidence for an …
various mental health conditions. Objective To evaluate whether there is evidence for an …
Neuroimaging-based markers of bipolar disorder: evidence from two meta-analyses
J Houenou, J Frommberger, S Carde… - Journal of affective …, 2011 - Elsevier
BACKGROUND: Bipolar disorder (BD) is often misdiagnosed or tardily detected, leading to
inadequate treatment and devastating consequences. The identification of objective …
inadequate treatment and devastating consequences. The identification of objective …
What we learn about bipolar disorder from large‐scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
MRI‐derived brain measures offer a link between genes, the environment and behavior and
have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of …
have been widely studied in bipolar disorder (BD). However, many neuroimaging studies of …
Neural correlates of the happy life: the amplitude of spontaneous low frequency fluctuations predicts subjective well-being
Subjective well-being is assumed to be distributed in the hedonic hotspots of subcortical and
cortical structures. However, the precise neural correlates underlying this construct …
cortical structures. However, the precise neural correlates underlying this construct …