A novel role of nogo proteins: regulating macrophages in inflammatory disease

N Zhang, Y Cui, Y Li, Y Mi - Cellular and Molecular Neurobiology, 2022 - Springer
Nogo proteins, also known as Reticulon-4, have been identified as myelin-derived inhibitors
of neurite outgrowth in the central nervous system (CNS). There are three Nogo variants …

Unveiling the modulation of Nogo receptor in neuroregeneration and plasticity: novel aspects and future horizon in a new frontier

BP Dave, KC Shah, MB Shah, MR Chorawala… - Biochemical …, 2023 - Elsevier
Neurodegenerative diseases (NDs) such as Alzheimer's, Parkinson's, Multiple Sclerosis,
Hereditary Spastic Paraplegia, and Amyotrophic Lateral Sclerosis have emerged as the …

Identification of novel senescent markers in small extracellular vesicles

T Misawa, K Hitomi, K Miyata, Y Tanaka, R Fujii… - International journal of …, 2023 - mdpi.com
Senescent cells exhibit several typical features, including the senescence-associated
secretory phenotype (SASP), promoting the secretion of various inflammatory proteins and …

Inflammation self‐limiting electrospun fibrous tape via regional immunity for deep soft tissue repair

Q Saiding, Z Cai, L Deng, W Cui - Small, 2022 - Wiley Online Library
Overexpression of inflammatory cytokines and chemokines occurs at deep soft tissue injury
sites impeding the inflammation self‐limiting and impairing the tissue remodeling process …

Microglial Nogo delays recovery following traumatic brain injury in mice

EJ Glotfelty, SC Hsueh, Q Claybourne, A Bedolla… - Glia, 2023 - Wiley Online Library
Abstract Nogo‐A, B, and C are well described members of the reticulon family of proteins,
most well known for their negative regulatory effects on central nervous system (CNS) …

Novel antidepressant-like properties of the fullerenol in an LPS-induced depressive mouse model

A Kong, T Liu, S Deng, S Xu, Y Luo, J Li, Z Du… - International …, 2023 - Elsevier
Depression is a common mental disease and is highly prevalent in populations.
Dysregulated neuroinflammation and concomitant-activated microglia are involved in the …

Enriched pathways of calcium regulation, cellular/oxidative stress, inflammation, and cell proliferation characterize gluteal muscle of standardbred horses between …

SJ Valberg, D Velez-Irizarry, ZJ Williams, ML Henry… - Genes, 2022 - mdpi.com
Certain Standardbred racehorses develop recurrent exertional rhabdomyolysis (RER-STD)
for unknown reasons. We compared gluteal muscle histopathology and gene/protein …

[HTML][HTML] Transcriptomic profiling of TLR-7-mediated immune-challenge in zebrafish embryos in the presence and absence of glucocorticoid-induced …

B Luckner, F Essfeld, SU Ayobahan, E Richling… - Ecotoxicology and …, 2023 - Elsevier
Although numerous studies imply a correlation between chemical contamination and an
impaired immunocompetence of wildlife populations, the assessment of immunomodulatory …

A Trinity Nano-Vaccine System with Spatiotemporal Immune Effect for the Adjuvant Cancer Therapy after Radiofrequency Ablation

M Li, A Jiang, H Han, M Chen, B Wang, Y Cheng… - ACS …, 2023 - ACS Publications
Cancer vaccine gains great attention with the advances in tumor immunology and
nanotechnology, but its long-term efficacy is restricted by the unsustainable immune activity …

Nogo-a and LINGO-1: two important targets for Remyelination and regeneration

I Kalafatakis, F Papagianni, K Theodorakis… - International Journal of …, 2023 - mdpi.com
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) that
causes progressive neurological disability in most patients due to neurodegeneration …