Role of inflammasomes in HIV-1 infection and treatment

X Jin, R Zhou, Y Huang - Trends in Molecular Medicine, 2022 - cell.com
Although combined antiretroviral therapy (cART) is effective in inhibiting human
immunodeficiency virus type 1 (HIV-1) replication, it does not eradicate the virus because …

New insights into HIV life cycle, Th1/Th2 shift during HIV infection and preferential virus infection of Th2 cells: Implications of early HIV treatment initiation and care

J Hokello, K Tyagi, RO Owor, AL Sharma, A Bhushan… - Life, 2024 - mdpi.com
The theory of immune regulation involves a homeostatic balance between T-helper 1 (Th1)
and T-helper 2 (Th2) responses. The Th1 and Th2 theories were introduced in 1986 as a …

Andrade-Oliveira Salvianolic Acid B Modulates Caspase-1–Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via Nrf2 Pathway

Y Pang, PC Zhang, RR Lu, HL Li, J Li, HX Fu… - Frontiers in …, 2020 - frontiersin.org
Acute kidney injury (AKI) is a serious disease characterized by a rapid decline in kidney
function. Oxidative stress is the primary pathogenesis of AKI. Salvianolic acid B (SalB), a …

Pyroptosis associated with immune reconstruction failure in HIV-1-infected patients receiving antiretroviral therapy: a cross-sectional study

X Lao, X Mei, J Zou, Q Xiao, Q Ning, X Xu… - BMC Infectious …, 2022 - Springer
Background Highly active anti-retroviral therapy (HAART) can successfully suppress human
immunodeficiency virus (HIV) viral replication and reconstruct immune function …

Cell pyroptosis in picornavirus and its potential for treating viral infection

Z Wang, H Yu, W Zhuang, J Chen… - Journal of Medical …, 2022 - Wiley Online Library
Cell pyroptosis has received increased attention due to the associations between innate
immunity and disease, and it has become a major focal point recently due to in‐depth …

T lymphocyte-mediated pyroptosis: A new regulatory mechanism in non-viral liver disease

W Xiong, Z Qian, X Mao, J Li - Clinics and Research in Hepatology and …, 2023 - Elsevier
T lymphocyte-mediated pyroptosis plays an important role in the development of non-viral
liver diseases. Pyroptosis as a programmed cell death process, has been a hot topic of …

[PDF][PDF] Caspase-1-dependent pyroptosis are associated with immune reconstruction failure in HIV-positive patients receiving antiretroviral therapy: a cross-sectional …

X Lao, X Mei, J Zou, Q Xiao, Q Ning, X Xu, C Zhang… - 2022 - scholar.archive.org
Background Highly Active Anti-Retroviral Therapy (HAART) can successfully suppress HIV-1
viral replication and reconstruct immune function reconstruction in HIV infected patients …

Modeling the Evolution of SIV Progenitor Viruses Ttowards HIV-1 and HIV-2 in a Humanized Mouse Surrogate Model

JZ Curlin - 2020 - search.proquest.com
Abstract Human Immunodeficiency Virus Type 1 (HIV-1) and Type 2 (HIV-2), the causative
agents of Acquired Immunodeficiency Syndrome (AIDS) first emerged in humans over the …

Étude de l'interactome et identification de nouvelles cibles de la protéine virale Vpr du VIH-1

JA Ferreira Barbosa - 2020 - papyrus.bib.umontreal.ca
Le virus de l'immunodéficience humaine de type 1 (VIH-1) est l'agent étiologique du SIDA,
un rétrovirus complexe encodant les protéines accessoires: Nef, Vif, Vpr et Vpu. La fonction …

Caractérisation immunologique des réservoirs des virus de l'immunodéficience humaine VIH-2 et VIH-1 dans les cellules immunocompétentes et étude des …

MS Diallo - 2020 - theses.hal.science
Les VIH-2 et VIH-1 diffèrent par leur pathogénicité. Pour mieux comprendre les mécanismes
de faible pathogénicité et de réplication du VIH-2, nous avons étudié les caractéristiques …