Alcohol use disorder (AUD) is a highly prevalent, comorbid, and disabling disorder. The
underlying mechanism of ethanol neurotoxicity and the involvement of oxidative stress is still …

Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) with a well-documented
role in the innate and adaptive immune responses. Interestingly, TLR activation has also …

Ethanol toxicity is a major public health problem that can cause damage to various organs in
the body by several mechanisms inducing oxidative stress, inflammation, and apoptosis …

Cells communication in response to extracellular or biophysical stimulus relies on
elaborated systems of signal transduction. In the course of most signal pathway, the …

In the current scenario, prolonged consumption of alcohol across the globe is upsurging an
appreciable number of patients with the risk of alcohol-associated liver diseases. According …

Alcohol ingestion is a widespread habituation that evolved along with a growing population,
altering physiological conditions through immunomodulatory function. There is much …

Background This systematic review synthesized evidence from randomized controlled trials
(RCTs) on the effects of integrated behavioral interventions for adults with alcohol use …

Objectives This study assessed the association between alcohol use patterns and the
prevalence of hypertension. Study design Data on alcohol use patterns and hypertension …

Abstract Substance Use Disorders (SUDs) manifest as persistent drug-seeking behavior
despite adverse consequences, with Alcohol Use Disorder (AUD) and Opioid Use Disorder …

Human heroin addicts and mice administered morphine for a 2 week period show a greatly
increased number of hypothalamic hypocretin (Hcrt or orexin) producing neurons with a …