The heme oxygenase (HO) system is believed to be a crucial mechanism for the nervous
system under stress conditions. HO degrades heme to carbon monoxide, iron, and …

Alzheimer's disease (AD) is the most common neurodegenerative disorders presenting with
the pathological hallmarks of amyloid plaques and tau tangles. Over the past few years …

The microtubule-associated protein tau aggregates into neurofibrillary tangles in Alzheimer's
disease (AD). The main type of aggregates, the paired helical filaments (PHF), incorporate …

Reactive astrocytes play an important role in the development of Alzheimer's disease (AD).
Here, we aimed to investigate the temporospatial relationships among monoamine oxidase …

Tau hyperphosphorylation and aggregation is a common feature of many dementia-causing
neurodegenerative diseases. Tau can be phosphorylated at up to 85 different sites, and …

Objective Epileptic spikes and seizures seem present early in the disease process of
Alzheimer's disease (AD). However, it is unclear how soluble and insoluble amyloid beta …

Tau is a microtubule-associated protein that plays crucial roles in physiology and
pathophysiology. In the realm of dementia, tau protein misfolding is associated with a wide …

Aberrant insulin signaling has been considered one of the risk factors for the development of
Alzheimer's disease (AD) and has drawn considerable attention from the research …

The formation of neurofibrillary tangles has been implicated as an important pathological
marker for Alzheimer's disease (AD). Studies have revealed that the inhibition of abnormal …

Transgenic models of familial Alzheimer's disease (AD) serve as valuable tools for probing
the molecular mechanisms associated with amyloid-beta (Aβ)-induced pathology. In this …